Two novel alkaloids named oleraciamide A (1) and oleraciamide B (2) were isolated from Portulaca oleracea L., and spectroscopic methods including 1D and 2D nuclear magnetic resonance and high-resolution electrospray ionisation quadrupole-time of flight mass spectrometer spectrometry techniques are employed to determine their structures. Oleraciamide A (1) was evaluated no cytotoxicity at concentrations up to 80 μM over 72 h against human adipose-derived stem cells (hADSCs) by CCK-8 method.
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http://dx.doi.org/10.1080/14786419.2017.1292507 | DOI Listing |
Plant Physiol Biochem
December 2024
Departamento de Producción Agrícola y Animal, Universidad Autónoma Metropolitana-Xochimilco, Calzada del Hueso 1100, Col. Villa Quietud, 04960, Ciudad de México, Mexico.
Purslane is a plant with high nutritional content that is mainly produced in the central part of Mexico. The nutritional content of purslane depends on various factors such as climatic and soil conditions, phenology, and fertilization. This article describes the H NMR metabolomics profiling of purslane in relation to fertilization at two harvest stages: C and C (27 and 42 days after emergence).
View Article and Find Full Text PDFNat Prod Res
January 2025
School of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, P.R. China.
Two new chromones, oleracone H () and oleracone I (), were isolated from L. and identified by UV, IR, UHPLC-ESI-QTOF/MS, 1D NMR, 2D NMR, and CD spectra. In 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical quenching assay, oleracone H () and oleracone I () presented scavenging activities with IC values (half maximal inhibitory concentration) of 16.
View Article and Find Full Text PDFVet Med Sci
January 2025
Department of Veterinary Tissue Engineering, College of Veterinary Medicine, Kyungpook National University, Daegu, Republic of Korea.
Benign prostatic hyperplasia (BPH) is a distressing health problem that can cause serious complications in aging men. Androgens are implicated in the causation of BPH. Portulaca oleracea (PO) is a natural product with diverse pharmacological effects.
View Article and Find Full Text PDFJ Sep Sci
January 2025
School of Pharmaceutical Sciences and Yunnan Provincial Key Laboratory of Pharmacology for Natural Medicines, Kunming Medical University, Kunming, Yunnan, People's Republic of China.
This study revealed the dynamic profiling of three main components of Portulaca oleracea L. in vivo in rats, namely allantoin (A), N-trans-feruloyl-3-methoxytyramine (M), and N-p-coumaroyltyramine (C). A sensitive and efficient UHPLC-ESI-Q-TOF/HRMS, including an optimized separation process, was applied to their qualitative and quantitative analysis.
View Article and Find Full Text PDFGenomics
December 2024
College of Pharmacy, Beihua University, 3999 Binjiang East Road, Jilin City, Jilin Province, 132013, China. Electronic address:
This study investigated the preventive and protective effects of Portulaca oleracea polysaccharides (PP) on Acute liver injury (ALI) in mice and its regulatory effects on intestinal microorganisms, and explored the underlying protective mechanisms. Initially, PP was administered, and then CCl4 was used to induce the mouse ALI model. Serum and liver markers were measured by ELISA.
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