Chemical constituents from Swertia mussotii Franch. (Gentianaceae).

Nat Prod Res

c Institute of Biomechanics and Medical Engineering , Tsinghua University, Beijing , China.

Published: July 2017

AI Article Synopsis

  • The study isolated 11 chemical compounds from the ethanolic extract of Swertia mussotii, using spectroscopic analysis and literature comparison for identification.
  • Four of these compounds (1, 2, 7, and 11) were discovered in the Swertia genus for the first time.
  • The research highlighted the chemotaxonomic relationship between S. mussotii and other Swertia species, suggesting that certain compounds could serve as important markers for classifying this genus.

Article Abstract

The chemical investigation of ethanolic extract from Swertia mussotii Franch. has resulted in the isolation of 11 compounds which were identified as Orcinol-β-D-glucoside (1), Shamimin (2), Mangiferin (3), Decussatin (4), Bellidifolin (5), Desmethylbellidifolin (6), Protocatechuic acid (7), 1,7-Dihydroxy-3,8-dimethoxyxanthone (8), 1,8-Dihydroxy-3,5-dimethoxyxanthone (9), 1-Hydroxy-3,5-dimethoxyxanthone (10), Telephioidin (11). The chemical structures of these compounds were identified by a combination of spectroscopic analysis and a comparison with those reported in literature. Among them, compounds 1, 2, 7 and 11 were isolated from the genus Swertia for the first time. Moreover, the chemotaxonomic significance of these compounds was summarised. The chemotaxonomic study suggests that there is a close chemotaxonomic relationship between S. mussotii and other species of Swertia, such as S. punicea, S. macrosperma, S. japonica, S. phragmitiphylla, S. chirayita, S. cordata and S. binchuanensis, with presence of compounds 3~6, 8~10. The xanthones and their glycosides may sever as important chemotaxonomic markers of Swertia genus.

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http://dx.doi.org/10.1080/14786419.2017.1286480DOI Listing

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