During the process of icogenin analog research, we obtained two cytotoxic steroids: compound 4 and compound 6 casually. Their in vitro antitumor activities were tested by the standard MTT assay. The results disclosed that compound 4 (IC = 3.65-6.90 μM) showed potential antitumor activities against HELA, KB cell lines and compound 6 (IC = 2.40-9.05 μM) showed potential antitumor activities against HELA, BGC-823, KB, A549, HCT-8 cell lines.
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| http://dx.doi.org/10.1080/10286020.2016.1228633 | DOI Listing |
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