The first total synthesis of anemarchalconyn and anemarcoumarin A.

J Asian Nat Prod Res

a Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province , Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu 610052 , China.

Published: September 2017

AI Article Synopsis

Article Abstract

Anemarchalconyn (1) and anemarcoumarin A (2), the natural bioactive compounds isolated from the rhizomes of Anemarrhena asphodeloides Bunge (Liliaceae), were first totally synthesized using easily available materials in short, convenient routes with overall yields of 32 and 48%.

Download full-text PDF

Source
http://dx.doi.org/10.1080/10286020.2016.1275583DOI Listing

Publication Analysis

Top Keywords

anemarchalconyn anemarcoumarin
8
total synthesis
4
synthesis anemarchalconyn
4
anemarcoumarin anemarchalconyn
4
anemarcoumarin natural
4
natural bioactive
4
bioactive compounds
4
compounds isolated
4
isolated rhizomes
4
rhizomes anemarrhena
4

Similar Publications

The first total synthesis of anemarchalconyn and anemarcoumarin A.

J Asian Nat Prod Res

September 2017

a Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province , Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu 610052 , China.

Anemarchalconyn (1) and anemarcoumarin A (2), the natural bioactive compounds isolated from the rhizomes of Anemarrhena asphodeloides Bunge (Liliaceae), were first totally synthesized using easily available materials in short, convenient routes with overall yields of 32 and 48%.

View Article and Find Full Text PDF

Identification of antiadipogenic constituents of the rhizomes of Anemarrhena asphodeloides.

J Nat Prod

October 2009

The Center for Cell Signaling & Drug Discovery Research, College of Pharmacy, Ewha Womans University, Seoul 120-750, Korea.

Three new phenolic compounds, (E)-4'-demethyl-6-methyleucomin (1), anemarcoumarin A (2), and anemarchalconyn (3), were isolated from an ethyl acetate extract of the rhizomes of Anemarrhena asphodeloides, together with seven known compounds (4-10). The structures of the new compounds (1-3) were determined on the basis of spectroscopic data interpretation. Compound 3 exhibited a potent inhibitory effect against the differentiation of preadipocyte 3T3-L1 cells with an IC50 value of 5.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!