Bringing light into gene regulation in hematopoietic stem cells by the Mediator complex.

Stem Cell Investig

Department of Biochemistry, Center for Molecular Biomedicine (CMB), Friedrich-Schiller-University Jena, 07745 Jena, Germany.

Published: February 2017

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334556PMC
http://dx.doi.org/10.21037/sci.2017.01.04DOI Listing

Publication Analysis

Top Keywords

bringing light
4
light gene
4
gene regulation
4
regulation hematopoietic
4
hematopoietic stem
4
stem cells
4
cells mediator
4
mediator complex
4
bringing
1
gene
1

Similar Publications

Effects of fish oil supplementation on bone turnover markers in depression: a pilot study.

Front Nutr

December 2024

The National Clinical Research Center for Mental Disorders and Beijing Key Laboratory of Mental Disorders and Beijing Institute for Brain Disorders Center of Schizophrenia, Beijing Anding Hospital, Capital Medical University, Beijing, China.

Background And Objective: There is a close correlation between bone loss, depression, and antidepressants. N-3 PUFA supplementation has been considered an effective add-on therapeutic approach in ameliorating bone loss and relieving depression. However, the adjunctive effect of n-3 PUFA on bone metabolism in participants with depression is still unknown.

View Article and Find Full Text PDF

Machine learning (ML) is a promising tool in assisting clinical decision-making for improving diagnosis and prognosis, especially in developing regions. It is often used with large samples, aggregating data from different regions and hospitals. However, it is unclear how this affects predictions in local centers.

View Article and Find Full Text PDF

Animal research is an essential contributor to the medical achievements of the last century. The first step of studying a disease in animals is the development of a model which is relevant to the clinical situation in humans. Thus, a good animal model is the sine qua non of the experimental research.

View Article and Find Full Text PDF

Background: Surgery and chemoradiotherapy are the main clinical treatment methods for colorectal cancer (CRC), but the prognosis is poor. The emergence of nanomedicine brings bright light to the treatment of CRC. However, there has not been a comprehensive and systematic analysis of CRC and nanomedicine by bibliometrics.

View Article and Find Full Text PDF

Aims: To evaluate antibody response to mRNA vaccine, identify subgroups with poor response and to determine long-term antibody durability in hematological patients.

Materials And Methods: We have vaccinated 292 patients with all hematological malignancies with a third dose of mRNA COMIRNATY vaccine with a 12-month follow-up period in our center in Ostrava, Czech Republic.

Results: Antibody response for the whole cohort exceeded 74% through the whole 12-month follow-up.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!