Phaeohyphomycosis is a rare but emerging disease caused by dematiaceous fungi. Here we describe the case of an immunosuppressed dog with disseminated phaeohyphomycosis secondary to infection. Regionally extensive infiltration of the paw pads, skin, myocardium, liver, renal interstitium and diaphragm was identified on histopathology. and were also cultured from multiple sites post-mortem. The dog was treated with fluconazole, itraconazole, terbinafine and liposomal amphotericin B, but was euthanized due to its poor prognosis after 12 days of therapy.
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http://dx.doi.org/10.1016/j.mmcr.2017.02.003 | DOI Listing |
Infect Dis Clin North Am
December 2024
Division of Infectious Diseases, Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center, 1300 Morris Park Avenue, Belfer 610, Bronx, NY 10461, USA. Electronic address:
Top Companion Anim Med
December 2024
Department of Specialty Medicine, Midwestern University, College of Veterinary Medicine, Glendale, AZ, USA.
Phaeohyphomycosis is an uncommon disease caused by dematiaceous fungi that is almost exclusively found in immunocompromised dogs. Here we describe the case of a dog treated with prednisone (1.1 mg/kg/day) and cyclosporine (11.
View Article and Find Full Text PDFMycopathologia
November 2024
Laboratoire de Parasitologie-Mycologie, Service de Parasitologie-Mycologie, AP-HP, Hôpital Saint-Louis, Université Paris-Cité, 1 Avenue Claude Vellefaux, 75010, Paris, France.
Introduction: Phaeohyphomycoses are uncommon and poorly understood opportunistic fungal infections, characterized by a wide spectrum of clinical manifestations ranging from localized skin lesions to disseminated disease. Most frequent genera are Alternaria, Cladophialophora, Exophiala or Curvularia. Less common ones, such as Verruconis gallopava, initially described as responsible of encephalitis of turkeys, pose significant challenges for diagnosis and treatment.
View Article and Find Full Text PDFVet Radiol Ultrasound
January 2025
Department of Radiology, MedVet Cincinnati, Fairfax, Ohio, USA.
A 3-year-old female spayed domestic shorthair cat with a history of immune-mediated hemolytic anemia, treated with cyclosporine and prednisolone, was presented for acute lethargy, anorexia, vomiting, and diarrhea. Abdominal ultrasound revealed multiple predominantly avascular hypo-anechoic nodules in the liver, kidneys, pancreas, and peritoneum. Fine needle aspirates and culture of the liver and kidney revealed abscessation caused by Cladophialophora.
View Article and Find Full Text PDFLancet Microbe
November 2024
Centre Hospitalo-Universitaire Régional de Tours, Department of Parasitology-Mycology-Tropical Medicine, Tours, France. Electronic address:
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