Background: Sri Lanka has recently completed an HIV prevention project for most-at-risk populations (MARP) under the Global Fund. The intervention includes delivery of a HIV prevention package (HPP) to men who have sex with men (MSM) that includes provision of: (1) knowledge about sexually transmitted infections (STI); (2) HIV knowledge; (3) MSM-tailored leaflets; (4) condom/dildo demonstration; (5) provision of condoms; and (6) clinic escorts. MSM who received services 1-5 in the HPP are defined as 'reached'. The final step is to escort the reached MSM to an STI clinic, and they are then defined as 'escorted'. This HPP was delivered to MSM through peer educators (PE) scattered in four highly populated districts in the country. Each PE has contact with another 15 peers forming a peer group (PG). However, in this model, a significant number of MSM do not take up the escorting step of the HPP. Therefore, the purpose of this paper is to analyse the factors associated with clinic escorts among MSM peers in the HIV prevention project.
Methods: All the MSM peers (699 MSM) registered and retained during the project period had been reached in 2013, 2014 and 2015 and were chosen from the web-based Monitoring and Evaluation information management system (MEIMS) for analysis. The sample was divided in to two groups based on escort status (escorted peers non-escorted peers). Variables were compared between the two groups for the hypothesis of difference to identify significant factors associated with clinic escorts.
Results: The study sample (699 MSM) represented four districts: Galle (37%), Colombo (35%), Gampaha (14%) and Kalutara (14%). Escort status depended on the district (<0.001), age group of MSM =0.008), level of education (=0.007) and urban/rural status (<0.001), duration of MSM behaviour (=0.018), experience of an HIV test during previous 12 months (=0.050), and recent receptive anal sex (=0.050).
Conclusions: Older MSM (>25 years), MSM living in urban and semi-urban areas, MSM (effeminate males), MSM with receptive behaviours as well as less-educated MSM were less likely to be escorted and needed some extra effort to improve escort rate among MSM. In addition, performance of PEs, field supervisors and coordinators was observed to be a major factor in improving escort rate.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337413 | PMC |
http://dx.doi.org/10.1016/S2055-6640(20)31098-0 | DOI Listing |
AIDS Behav
January 2025
Department of Medicine, University of Alabama at Birmingham, 845 19th Street South, Bevill Biomedical Research Building, Room 256D, Birmingham, AL, 35294-2170, USA.
Antiretroviral therapy (ART) use and HIV suppression among people living with HIV (PLHIV) are critical for HIV control and prevention. Extreme restrictions on movement early during the COVID-19 pandemic in Uganda may have impeded the ability to initiate and sustain access to and use of ART. From our stepped-wedge cluster-randomized trial of an integrated PrEP and ART intervention for HIV-serodifferent couples at 12 ART clinics in Uganda, we identified participants who enrolled and had a 6-month post-ART initiation viral load measured before the beginning of the first COVID-19 lockdown (Period 1), participants whose enrollment and 6-month viral load measurement straddled pre-COVID and COVID lockdown times (Period 2), and participants whose enrollment and 6-month viral load were quantified entirely during COVID-19 (Period 3).
View Article and Find Full Text PDFAIDS Behav
January 2025
Aix Marseille Univ, IRD, Inserm, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de l'Information Médicale, ISSPAM, Marseille, France.
High HIV prevalence in Sub-Saharan African (SSA) in men who have sex with men (MSM) leads to greater risk for their wives and other steady female partners because of prolonged exposure. To provide insights into the context possibly contributing to the risk of HIV transmission from MSM to women, our mixed-method synthesis about MSM' marriage and steady relationships with cisgender women aimed to: (i) assess the extent of engagement in steady relationships with women and in risky behaviors with these women across SSA's four regions; (ii) explore the underlying dynamics within these relationships by gathering qualitative information. We used quantitative and qualitative data specifically pertaining to related to marriage or other steady relationships with women from a systematic review on men who have sex with both men and women (MSMW) in SSA (PROSPERO-CRD42021237836).
View Article and Find Full Text PDFAnal Chim Acta
January 2025
Department of Laboratory Medicine, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, People's Republic of China; Wuhan Research Center for Infectious Diseases and Cancer, Chinese Academy of Medical Sciences, Wuhan, People's Republic of China; Hubei Engineering Center for Infectious Disease Prevention, Control and Treatment, Wuhan, People's Republic of China. Electronic address:
Background: In current years, the CRISPR (clustered regularly interspaced short palindromic repeats) based strategies have emerged as the most promising molecular tool in the field of gene editing, intracellular imaging, transcriptional regulation and biosensing. However, the recent CRISPR-based diagnostic technologies still require the incorporation of other amplification strategies (such as polymerase chain reaction) to improve the cis/trans cleavage activity of Cas12a, which complicates the detection workflow and lack of a uniform compatible system to respond to the target in one pot.
Results: To better fully-functioning CRISPR/Cas12a, we reported a novel technique for straightforward nucleic acid detection by incorporating enzyme-responsive steric hindrance-based branched inhibitors with CRISPR/AsCas12a methodology.
Contraception
January 2025
UNDP-UNFPA-UNICEF-WHO-World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP) Department of Sexual and Reproductive Health and Research (SRH) World Health Organization, Geneva, Switzerland. Electronic address:
The right to health and other health-related human rights are legally binding commitments enshrined in international human rights instruments. While these positions are known and ratified by policy makers, little has been done to actualize men's sexual and reproductive health (SRH) as an integral part of attaining these important global goals. Not addressing men's SRH over and above supporting their female partners sustains the sexual and reproductive risks and burdens that women must bear.
View Article and Find Full Text PDFLancet HIV
January 2025
Division of Infectious Diseases, Hennepin Healthcare, Minneapolis, MN, USA; University of Minnesota, Minneapolis, MN, USA. Electronic address:
Despite advancements in existing antiretroviral-based prevention strategies, including daily oral, locally acting, and injectable options, there is a pressing need for more inclusive and flexible event-driven pre-exposure prophylaxis (PrEP) strategies for all. Event-driven or intermittent dosing of PrEP in populations beyond cisgender men who have sex with men would offer a promising alternative by fitting prevention into the diverse lifestyles of affected populations and thereby advancing health equity. Evidence from PrEP clinical trials, pharmacokinetic studies, modelling studies, and real-world observational research suggests that event-driven PrEP could be a flexible and inclusive option, yet optimal dosing has not been established across sex and gender spectrums.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!