Mosquito-borne diseases account for multiple public health challenges in our modern world. The international health community has seen a number of mosquito-borne diseases come to the forefront in recent years, including West Nile virus, Chikungunya virus, and currently, Zika virus. Predicting the spread of mosquito-borne disease can aid early decision support for when and how to employ public health interventions within a community; however, accurate and fast predictions, months into the future, are difficult to achieve in urgent scenarios, particularly when little information is known about infection rates. New sources of information including social media have been proposed to accelerate the development of predictive models of disease progression. In this research, we adapted a previously described model for the spread of mosquito-borne disease using open intelligence sources. The novel implementation of a mixed-model for mosquito-borne disease was capable of being executed in minimal runtime. The results indicate that this model yields fast and relevant results with acceptable margins of error.
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Parasit Vectors
December 2024
Institut de Recherche Biomédicale des Armées (IRBA), Unité de Parasitologie et Entomologie, Marseille, France.
Background: The risk of mosquito-borne disease transmission is increasing in temperate climates with the colonization and proliferation of the Asian tiger mosquito vector Aedes albopictus and the rapid mass transport of passengers returning from tropical regions where viruses are endemic. The prevention of major Aedes-borne viruses heavily relies on the use of insecticides for vector control, mainly pyrethroids. In Europe, only deltamethrin is authorized.
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December 2024
Center for Global Health and Inter-Disciplinary Research, College of Public Health, University of South Florida, Tampa, FL, USA.
Successful transmission of Plasmodium falciparum from one person to another relies on the complete intraerythrocytic development of non-pathogenic sexual gametocytes infectious for anopheline mosquitoes. Understanding the genetic factors that regulate gametocyte development is vital for identifying transmission-blocking targets in the malaria parasite life cycle. Toward this end, we conducted a forward genetic study to characterize the development of gametocytes from sexual commitment to mature stage V.
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December 2024
Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Dengue fever poses a significant public health burden in tropical regions, including Thailand, where periodic epidemics strain healthcare resources. Effective disease surveillance is essential for timely intervention and resource allocation. Various methods exist for spatiotemporal cluster detection, but their comparative performance remains unclear.
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December 2024
Department of Mathematics, Ghazni University, Ghazni, Afghanistan.
The current manuscript presents a mathematical model of dengue fever transmission with an asymptomatic compartment to capture infection dynamics in the presence of uncertainty. The model is fuzzified using triangular fuzzy numbers (TFNs) approach. The obtained fuzzy-fractional dengue model is then solved and analyzed through fuzzy extension of modified residual power series algorithm, which utilizes residual power series along with Laplace transform.
View Article and Find Full Text PDFCharacterization of serological responses to Plasmodium falciparum (Pf) is of interest to understand disease burden and transmission dynamics; however, their interpretation is challenging. Dried blood spots from 30,815 participants aged 6 months to 15 years from the 2018 Nigeria HIV/AIDS Indicator and Impact Survey were analyzed by multiplex bead-based assay to measure immunoglobulin G (IgG) to Pf-stage-specific MSP-1, AMA-1, GLURPR0, LSA-1, and CSP. These IgG levels were analyzed by principal component analysis (PCA).
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