Brief episodes of momentarily falling asleep - microsleeps - can have fatal consequences, especially in the transportation sector. In this study, the EEG data of eight subjects, while performing a 1-D tracking task, were used to predict imminent microsleeps. A novel algorithm was developed to improve the accuracy of microsleep identification from two independent measures: tracking performance and face-video. The uncertain labels of gold-standard were then pruned out. Additionally, the state of microsleep at 0.25 s ahead was continuously predicted. Log-power spectral features were then extracted from EEG data. The most relevant features were selected by mutual information. Leave-one-subject-out was performed to test the classifier on an independent subject and this procedure was done for all the subjects. Two oversampling methods, synthetic minority oversampling technique (SMOTE) and adaptive sampling (ADASYN), were utilized to improve the training in the presence of imbalanced data. The best average area under the curve of receiver operating characteristic (AUCroc) of 0.90 was achieved using SMOTE oversampling over a 5.25 s window length, with a corresponding geometric mean (GM) of 0.74. ADASYN oversampling achieved the best sensitivity of 0.76 (cf. 0.70 for SMOTE), but with a lower specificity of 0.77 (cf. 0.86 for SMOTE).
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http://dx.doi.org/10.1109/EMBC.2016.7591764 | DOI Listing |
Neurosci Biobehav Rev
December 2024
Interdisciplinary Neuroscience Program, University of Nevada, Las Vegas; Department of Psychology, University of Nevada, Las Vegas.
This review highlights the crucial role of neuroelectrophysiology in illuminating the mechanisms underlying Alzheimer's disease (AD) pathogenesis and progression, emphasizing its potential to inform the development of effective treatments. Electrophysiological techniques provide unparalleled precision in exploring the intricate networks affected by AD, offering insights into the synaptic dysfunction, network alterations, and oscillatory abnormalities that characterize the disease. We discuss a range of electrophysiological methods, from non-invasive clinical techniques like electroencephalography and magnetoencephalography to invasive recordings in animal models.
View Article and Find Full Text PDFAutism Res
December 2024
Psychiatry and Addictology Department, CIUSSS-NIM Research Center, University of Montreal, Montreal, Quebec, Canada.
Child-directed speech (CDS), which amplifies acoustic and social features of speech during interactions with young children, promotes typical phonetic and language development. In autism, both behavioral and brain data indicate reduced sensitivity to human speech, which predicts absent, decreased, or atypical benefits of exaggerated speech signals such as CDS. This study investigates the impact of exaggerated fundamental frequency (F0) and voice-onset time on the neural processing of speech sounds in 22 Chinese-speaking autistic children aged 2-7 years old with a history of speech delays, compared with 25 typically developing (TD) peers.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Introduction: Down Syndrome Regression Disorder (DSRD) is a neuropsychiatric condition causing insomnia, catatonia, encephalopathy, and obsessive-compulsive behavior in otherwise healthy individuals with Down syndrome (DS). Smaller cohorts have identified heterogenous diagnostic abnormalities which have predicted immunotherapy responsiveness although pattern analysis in a large cohort has never been performed.
Methods: A multi-center, retrospective study of individuals with DSRD was performed.
Sci Rep
December 2024
Brain Dynamics Lab, Interdisciplinary Center of Biomedical and Engineering Research for Health, Universidad de Valparaíso, Valparaíso, Chile.
Multi-state metastability in neuroimaging signals reflects the brain's flexibility to transition between network configurations in response to changing environments or tasks. We modeled these dynamics with a Kuramoto network of 90 nodes oscillating at an intrinsic frequency of 40 Hz, interconnected using human brain structural connectivity strengths and delays. We simulated this model for 30 min to generate multi-state metastability.
View Article and Find Full Text PDFJ Pers Med
December 2024
Department of Medical Education, Catolica Medical School, Universidade Católica Portuguesa, 1649-023 Oeiras, Portugal.
Transcranial Magnetic Stimulation-Electroencephalography (TMS-EEG) is a non-operative technique that allows for magnetic cortical stimulation (TMS) and analysis of the electrical currents generated in the brain (EEG). Despite the regular utilization of both techniques independently, little is known about the potential impact of their combination in neurosurgical practice. This scoping review, conducted following PRISMA guidelines, focused on TMS-EEG in epilepsy, neuro-oncology, and general neurosurgery.
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