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Prophylactic barrage laser in patients with previous vitreous loss during cataract surgery: a randomized clinical trial.
BMC Ophthalmol
January 2025
Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Background: One of the significant challenges that can arise during cataract surgery is the occurrence of posterior capsule rupture (PCR) and vitreous loss. It may result in different complications including cystoid macular edema, endophthalmitis, glaucoma, and considerably retinal detachment which consequently contributes to poor functional outcomes.
Methods: This study was a prospective double blinded randomized clinical trial including 42 patients with previous complicated cataract surgery including posterior capsular rupture and consequently vitreous loss that anterior vitrectomy was done for them.
[Paying attention to the management of blinding complications caused by early-onset high myopia in children].
Zhonghua Yan Ke Za Zhi
January 2025
Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology ＆ Visual Sciences, Beijing100730, China.
Article Synopsis
- Early-onset high myopia (eoHM) is a serious eye condition in preschool children that can hinder visual development and lead to complications like retinal detachment.
- Effective management of eoHM is essential to prevent vision loss and support overall child development.
- The article aims to highlight the importance of early diagnosis and long-term care for children with eoHM, serving as a guide for healthcare professionals.
The Orbitomalar Ligament: A Cleavage Plane in Oculofacial Trauma.
Ophthalmic Plast Reconstr Surg
December 2024
Section of Ophthalmology, Department of Surgery.
We describe an oculofacial injury phenotype manifesting as a cleavage plane following the orbitomalar ligament in 5 cases. Across these cases, curvilinear wounds followed the course of the orbitomalar ligament, running clean planes through orbicularis oculi down to the infraorbital rim and arcus marginalis. One case involved bilateral orbitomalar ligaments, and 1 case involved the inferior canaliculus.
View Article and Find Full Text PDFSubconjunctival trypsin injection for anterior chamber fibrin exudates in eyes with globe rupture following vitrectomy.
Int J Ophthalmol
November 2024
Department of Retina and Vitreous, Jingliang Eye Hospital, Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.
Article Synopsis
- The study aimed to compare the safety and effectiveness of subconjunctival injections of trypsin versus dexamethasone (DEX) for treating fibrin exudates in patients after globe rupture repair.
- A total of 52 patients were treated with either trypsin or DEX, with results indicating that both treatments led to similar levels of exudate absorption, but trypsin had a quicker absorption time and was less irritating for patients.
- Overall, trypsin was found to be a more comfortable treatment option than DEX, with no adverse effects reported and stable intraocular pressure.
Atorvastatin Alleviates Age-Related Macular Degeneration via AIM2-Regulated Pyroptosis.
Inflammation
October 2024
Chongqing Key Laboratory for the Prevention and Treatment of Major Blinding Eye Diseases, Chongqing Eye Institute, The First Affiliated Hospital of Chongqing Medical University, Chongqing Branch of National Clinical Research Center for Ocular Diseases, Chongqing, 400016, China.
The underlying causes of age-related macular degeneration (AMD) remain elusive and treatment options of it are limited, while atorvastatin (AT) is expected to improve AMD. Our study sought to uncover the specific mechanisms that initiate pyroptosis in AMD and elucidate whether AT ameliorates Aβ1-40-induced retinal damage by inhibiting pyroptosis. An animal model of AMD was triggered by Aβ1-40, and the therapeutic efficacy of AT was evaluated by hematoxylin and eosin staining (H&E), Optical Coherence Tomography (OCT), Electroretinogram (ERG) and other methods.
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