Background: Laparoscopic upper abdominal surgery can cause spontaneous respiration due to diaphragmatic stimulation and intra-abdominal CO inflation. Therefore, sufficient muscle relaxation is necessary for a safe surgical environment.
Methods: We investigated if the combination of rocuronium and cisatracurium can counteract the delayed onset of cisatracurium's action and delayed recovery of muscle relaxation and whether the dosage of rocuronium, which is metabolized hepatically, can be reduced. A total of 75 patients scheduled for laparoscopic cholecystectomy with an American Society of Anesthesiology physical status I-II, in the age range of 20-60 years, and with a 20-30 kg/m body mass index were included in the study.
Results: The patients were divided into the following groups: combination group (Group RC, rocuronium 0.3 mg/kg and cisatracurium 0.05 mg/kg), rocuronium group (Group R, rocuronium 0.6 mg/kg), and cisatracurium group (Group C, cisatracurium 0.1 mg/kg), and the onset, 25% duration, recovery index, and addition/time ratio were measured. Patients in Group RC exhibited a significantly different addition/time ratio compared with patients in the other two groups (p = 0.003).
Conclusion: During laparoscopic cholecystectomy, the 95% effective dose of rocuronium in combination with cisatracurium is expected to provide a sufficient muscle relaxant effect.
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http://dx.doi.org/10.15280/jlm.2017.7.1.35 | DOI Listing |
Cureus
December 2024
General Surgery, Sunshine Coast University Hospital, Birtinya, AUS.
Cholecystectomy is one of the most commonly performed surgical operations worldwide. A rare complication following this procedure is the migration of surgical clips used to secure the cystic duct and artery. Herein, we report the migration of a metallic surgical clip into the common bile duct of a 75-year-old gentleman who underwent a laparoscopic cholecystectomy 24 years prior.
View Article and Find Full Text PDFJ Surg Case Rep
January 2025
Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Laparoscopic cholecystectomy is the preferred method for treating acute cholecystitis. Although the incidence of postoperative infections in laparoscopic cholecystectomy is low, serious postoperative surgical site infections are still reported. Hepatic abscesses, particularly fungal, can occur post-cholecystectomy leading to significant mortality and morbidity.
View Article and Find Full Text PDFBiliary sepsis, characterized by contamination and infection of the biliary tract, poses a serious medical issue with detrimental effects on the patients. While cholecystectomy is the usual treatment for symptomatic gallstones, the most desirable management approach for biliary sepsis remains debated, prompting a scientific evaluation of the long-term effects of cholecystectomy. To compare the long-term outcomes of biliary sepsis in patients undergoing cholecystectomy versus conservative management (CM), this study will systematically review the existing literature to clarify differences in recurrence rates, complication rates, and overall survival.
View Article and Find Full Text PDFKhirurgiia (Mosk)
December 2024
Botkin Municipal Clinical Hospital, Moscow, Russia.
Objective: To estimate the efficacy of transversus abdominis plane block (TAP block) for laparoscopic cholecystectomy (LCE) in short-term acute care hospital.
Material And Methods: There were 443 LCEs under interfascial blockade in short-term acute care hospital between 2018 and 2021. For retrospective assessment of benefits of this analgesia, we distinguished the control group consisting of 384 patients who underwent LCE in a 24h-hospital without TAP block.
Wiad Lek
December 2024
BOGOMOLETS NATIONAL MEDICAL UNIVERSITY, KYIV, UKRAINE; CNE ≪KYIV CITY CLINICAL HOSPITAL OF EMERGENCY CARE≫, KYIV, UKRAINE.
Objective: Aim: To identify and evaluate the risk factors affecting the success of single-stage laparoscopic treatment for choledocholithiasis.
Patients And Methods: Materials and Methods: We performed a retrospective analysis of treatment of 139 patients who underwent single-stage laparoscopic CBD exploration and cholecystectomy from 2018 to 2024. Data were analysed by the use of multivariate logistic regression to identify significant predictors of negative outcomes.
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