Background: Proliferation of terms describing the science of effectively promoting and supporting the use of research evidence in healthcare policy and practice has hampered understanding and development of the field. To address this, an international Terminology Working Group developed and published a simplified framework of interventions to promote and integrate evidence into health practices, systems, and policies. This paper presents results of validation work and a second international workgroup meeting, culminating in the updated AIMD framework [Aims, Ingredients, Mechanism, Delivery].
Methods: Framework validity was evaluated against terminology schemas (n = 51); primary studies (n = 37); and reporting guidelines (n = 10). Framework components were independently categorized as fully represented, partly represented, or absent by two researchers. Opportunities to refine the framework were systematically recorded. A meeting of the expanded international Terminology Working Group updated the framework by reviewing and deliberating upon validation findings and refinement proposals.
Results: There was variation in representativeness of the components across the three types of literature, in particular for the component 'causal mechanisms'. Analysis of primary studies revealed that representativeness of this concept lowered from 92 to 68% if only explicit, rather than explicit and non-explicit references to causal mechanisms were included. All components were very well represented in reporting guidelines, however the level of description of these was lower than in other types of literature. Twelve opportunities were identified to improve the framework, 9 of which were operationalized at the meeting. The updated AIMD framework comprises four components: (1) Aims: what do you want your intervention to achieve and for whom? (2) Ingredients: what comprises the intervention? (3) Mechanisms: how do you propose the intervention will work? and (4) Delivery: how will you deliver the intervention?
Conclusions: The draft simplified framework was validated with reference to a wide range of relevant literature and improvements have enhanced useability. The AIMD framework could aid in the promotion of evidence into practice, remove barriers to understanding how interventions work, enhance communication of interventions and support knowledge synthesis. Future work needs to focus on developing and testing resources and educational initiatives to optimize use of the AIMD framework in collaboration with relevant end-user groups.
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http://dx.doi.org/10.1186/s12874-017-0314-8 | DOI Listing |
Nat Commun
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School of Materials Science and Engineering, Peking University, Beijing, P.R. China.
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January 2025
CAS Key Laboratory of Urban Pollutant Conversion, Department of Environmental Science and Engineering, University of Science and Technology of China, Hefei 230026, China.
The introduction of structural defects can improve the charge separation efficiency of metal-organic frameworks (MOFs)-based photocatalysts, which however come with suboptimal decontamination performance, due to steric hindrance and limited binding capacity of the involved modulators. In this work, hydroxyl group capturing the advantages of both worlds was utilized as new modulator to improve the photocatalytic performance of Fe-based defective MOFs. Benefited from its low steric effect and strong coordination bonding capability, hydroxyl-induced defects in Fe-MOF contributed to a nearly 8-fold increase of rate constant for the photocatalytic removal of hexavalent chromium (Cr(VI)) compared to that of pristine one, which also exceeded the defective one induced by acetic acid as modulator.
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December 2024
State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Haihe Laboratory of Sustainable Chemical Transformations, Nankai University, Tianjin, 300071, P. R. China.
Circularly polarized luminescence (CPL) in inorganic quantum dots (QDs) represents a burgeoning and dynamic research domain, offering immense potential across a spectrum of applications, including three-dimensional displays, optical data storage, asymmetric catalysis, and chiral sensing. However, the persistent trade-off between fluorescence brightness and the emission dissymmetry factor highlights the nascent stage of current research. This review delves into the synthesis methodologies of CPL QDs, providing an exhaustive analysis of existing approaches and the resulting material properties.
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November 2024
Material, Physical, and Chemical Sciences Center, Sandia National Laboratories, Albuquerque, New Mexico 87123, United States.
Volatile organic compounds (VOCs) are harmful chemicals that are found in minute quantities in the atmosphere and are emitted from a variety of industrial and biological processes. They can be harmful to breathe or serve as biomarkers for disease detection. Therefore, capture and detection of VOCs is important.
View Article and Find Full Text PDFPhys Chem Chem Phys
November 2024
School of Physics, East China University of Science and Technology, Shanghai, 200237, China.
Crystal materials can exhibit novel properties under high pressure, which are completely different from properties under ambient conditions. Water ice has an exceptionally rich phase diagram with at least 20 known crystalline ice phases from experiments, where the high-pressure ice X and ice XVIII behave as an ionic state and a superionic state, respectively. Thus, the ice structures stabilized under high pressure are very likely to possess other novel properties.
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