A Phase II trial of high-dose chlorambucil at 108 mg/m2 was undertaken in non-small cell lung cancer. No complete or partial objective responses were observed, and significant toxicity, including nausea, vomiting, and seizures, was noted. Chlorambucil at this dose and schedule of administration is not recommended for the treatment of non-small cell lung cancer.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/00000421-198712000-00011 | DOI Listing |
Publication Analysis
Top Keywords
non-small cell
12
cell lung
12
lung cancer
12
phase trial
8
trial chlorambucil
4
chlorambucil non-small
4
cancer phase
4
trial high-dose
4
high-dose chlorambucil
4
chlorambucil 108
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!