The study of cancers of the vulva, first of all, attempts to classify precancerous lesions of the external genital apparatus. The proceedings of the ISSVD were carried out here in 1975. Clinical, epidemiological and viral arguments of HPV and HSV have been considered in order to demonstrate their responsibility in neoplasms of the vulva. However, HPV seems the main cocarcinogen. Cancers of the vulva appear, therefore, as a true sexually transmitted disease and the authors emphasize a simultaneous monitoring of the cervix and the male genital apparatus.
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Curr Oncol
December 2024
Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Vulvar cancer is one of the rarest gynecological malignancies. The development of this condition can be associated with either dysplasia linked to human papillomavirus (HPV), primarily affecting younger women, or vulvar dermatoses such as lichen sclerosus, which predominantly affect older women. Over the last decade, the incidence of vulvar cancer has risen by 0.
View Article and Find Full Text PDFAm J Dermatopathol
February 2025
Departments of Dermatology and Pathology, School of Medicine, Wake Forest University, Medical Center BLVD, Winston Salem, NC.
Primary vulvar carcinomas are rare and constitute a diverse group of neoplasms. These primary tumors are typically classified based on their presumed tissue of origin or histological characteristics. Among these, carcinomas of sweat gland origin are particularly significant.
View Article and Find Full Text PDFGynecol Oncol Rep
February 2025
People's Hospital of China Medical University, Department of Gynecology, People's Hospital of Liaoning Province, Shenyang, China.
Background: Keratoacanthoma is a relatively rare skin tumor, with vulvar keratoacanthoma being even more uncommon. Although the majority of keratoacanthomas exhibit a benign course, a subset of cases may show features of malignant potential, such as marginal invasion and recurrence.
Case: An 82-year-old female presented with a rapidly growing exophytic lesion on the left vulva, measuring 1.
Iran J Med Sci
December 2024
Department of Urology, Hasheminejad Kidney Center, Iran University of Medical Sciences, Tehran, Iran.
Background: Labial adhesion (LA) is a total or partial labial fusion mostly seen in pre-pubertal children and is rare in premenopausal and postmenopausal periods. This review aimed to evaluate risk factors for labial fusion and the recurrence rate following surgical intervention in postmenopausal women.
Methods: According to PRISMA guidelines, international databases including Embase, World Cat, Web of Science, Scopus, Dimension, Open Grey, Cochrane, Google Scholar, and also PubMed gateway for PMC and MEDLINE were searched.
Eur J Radiol
January 2025
Department of Diagnostic Imaging, Radiation Oncology and Hematology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy. Electronic address:
Pathologies of the vulva encompass a wide range of mesenchymal and epithelial benign and malignant lesions. Suspicion is raised by non-specific symptoms or clinical findings detected during routine gynecological examinations, and histopathology is essential for the diagnosis. The role of imaging has often been limited, but it can be essential in guiding treatment and, in some cases, in helping differential diagnosis.
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