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Recent Progress in Myocardial Perfusion Imaging Techniques.
Nucl Med Mol Imaging
December 2024
Department of Nuclear Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Article Synopsis
- Nuclear cardiology has advanced rapidly, particularly in myocardial perfusion imaging (MPI) since the 1970s, which is vital for assessing and managing coronary artery disease.
- Recent innovations include the development of gamma cameras with cadmium zinc telluride (CZT) systems and enhancements in software, as well as ongoing studies into new radiopharmaceuticals for positron emission tomography (PET)-MPI.
- Despite these advancements, challenges like high equipment and examination costs, along with limited accessibility, pose significant barriers to the practical use of these technologies in nuclear medicine.
Impact of CT attenuation correction on viable myocardium detection in combined SPECT and PET/CT: A retrospective cohort study.
Medicine (Baltimore)
October 2024
Department of Nuclear Medicine, TEDA International Cardiovascular Hospital, Tianjin University, Tianjin, P.R. China.
The influence of computed tomography attenuation correction (CTAC) on the accuracy of diagnosing viable myocardium using Tc-99m-MIBI dedicated cardiac cadmium-zinc-telluride (CZT) single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) combined with F-18-FDG Positron Emission Tomography/Computed Tomography (PET/CT) metabolic imaging, compared with conventional SPECT MPI, remains to be fully elucidated. To evaluate the impact of CTAC on the accuracy of diagnosing viable myocardium using Tc-99m-MIBI dedicated cardiac CZT SPECT MPI combined with F-18-FDG PET/CT, compared to conventional SPECT MPI. 193 patients underwent CZT SPECT and F-18-FDG PET/CT imaging, while 39 patients underwent conventional SPECT and F-18-FDG PET/CT imaging, with both groups utilizing CT for attenuation correction.
View Article and Find Full Text PDFAnalysis of Myocardial Flow Reserve Using the CZT Camera. Additional Value to Perfusion and Functional Information in Identifying the Cause of Chest Discomfort.
Arq Bras Cardiol
October 2024
Instituto Dante Pazzanese de Cardiologia, São Paulo, SP - Brasil.
Value of Ischemia and Coronary Anatomy in Prognosis and Guiding Revascularization Among Patients With Stable Ischemic Heart Disease.
Circ Cardiovasc Imaging
September 2024
Department of Imaging, Fondazione Toscana Gabriele Monasterio, Pisa, Italy (A. Giorgetti, A. Gimelli).
Background: The value of physiological ischemia versus anatomic severity of disease for prognosis and management of patients with stable coronary artery disease (CAD) is widely debated.
Methods: A total of 1764 patients who had rest-stress cadmium-zinc-telluride single-photon emission computed tomography myocardial perfusion imaging and angiography (invasive or computed tomography) were prospectively enrolled and followed for cardiac death/nonfatal myocardial infarction. The CAD prognostic index (CADPI) was used to quantify the extent and severity of angiographic disease.
Characterization of myocardial perfusion imaging systems - an extension of quality metrics.
Phys Med
September 2024
Medical Physics and Radiation Protection Department, University Hospital Rijeka, Croatia; Department of Medical Physics and Biophysics, Faculty of Medicine, University of Rijeka, Croatia. Electronic address:
Purpose: The aim of this study was to evaluate the performance of myocardial perfusion imaging (MPI) systems in detecting perfusion defects (PDs). The defect perfusion index (DPI) was introduced to extend and further advance the current MPI quality metrics.
Methods: An anthropomorphic phantom simulating normal and pathological myocardial perfusion conditions was imaged by various NaI-crystal detector systems with and without corrections for scatter (SC) and attenuation (AC) (Symbia, Symbia + SC, Symbia IQ + SCAC, Symbia IQ), and cadmium-zinc-telluride detector systems without corrections (DSPECT, D530c).
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