Aim: To evaluate the corneal cell morphology of new keratoconus patients wearing two different types of rigid gas-permeable (RGP) contact lenses for 1y.
Methods: Thirty nine eyes of 39 new keratoconus patients were selected and randomly fitted with two types of RGP contact lenses. Group 1 had 21 eyes with regular rigid gas-permeable (RRGP) contact lens and rest 18 eyes were in group 2 with specially designed rigid gas-permeable (SRGP) contact lens. Corneal cell morphology was evaluated using a slit scanning confocal microscope at no-lens wear and after 1y of contact lens wearing.
Results: After 1y of contact lens wearing in group 1, the mean anterior and posterior stromal keratocyte density were significantly less (=0.006 and =0.001, respectively) compared to no-lens wear. The mean cell area of anterior and posterior stromal keratocyte were also significantly different (=0.005 and =0.001) from no-lens wear. The anterior and posterior stromal haze increased by 18.74% and 23.81%, respectively after 1y of contact lens wearing. Whereas in group 2, statistically significant changes were observed only in cell density & area of anterior stroma (=0.001 and =0.001, respectively) after 1y. While, level of anterior and posterior stromal haze increased by 16.67% and 11.11% after 1y of contact lens wearing. Polymegathism and pleomorphism also increased after 1y of contact lens wearing in both the contact lens groups.
Conclusion: Confocal microscopy observation shows the significant alterations in corneal cell morphology of keratoconic corneas wearing contact lenses especially in group 1. The type of contact lens must be carefully selected to minimize changes in corneal cell morphology.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313545 | PMC |
| http://dx.doi.org/10.18240/ijo.2017.02.08 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Purpose: This study compares and evaluates the parameters of iridotrabecular contact (ITC) in patients with primary angle closure disease (PACD) with natural lenses and pseudophakia based on anterior segment imaging data from swept-source optical coherence tomography (SS-OCT).
Material And Methods: This retrospective study analyzed data from 92 patients aged 32 to 89 years, and included 56 patients with PACD (43 with natural lenses and 13 with pseudophakia) and 36 in the control group (21 with natural lenses and 15 with pseudophakia). All participants underwent SS-OCT (CASIA2; Tomey Corporation, Japan), which included an assessment of the ITC Index and ITC Area.
In this Prentice Medal Award lecture, I shall recount my career in vision science in the context of three types of inspiration-"being inspired," "personal inspiration," and "inspiring others." My research has derived inspiration from a variety of sources, such as contemporary and historical research doyens in the ophthalmic field and beyond, artists, Greek philosophers, and abstract constructs such as principles and adages. A given moment of inspiration can range from being a profound experience to a subtle realization during a quiet moment of reflection.
View Article and Find Full Text PDFEvaluation of change in the contact of IOL with the posterior capsule with respect to the orientation of haptics of the IOL using intraoperative spectral domain optical coherence tomography.
Indian J Ophthalmol
December 2024
University Eye Clinic Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands.
Purpose: To study change in the contact of intraocular lens (IOL) with the posterior capsule with respect to the vertical versus horizontal orientation of the haptic-optic junction of the IOL using intraoperative spectral domain optical coherence tomography (SD-OCT).
Methods: Fifty eyes of 50 patients with senile immature cataract underwent topical phacoemulsification procedure with implantation of a monofocal IOL by a single experienced surgeon. The Rescan 700 SD-OCT system was used for intraoperative imaging.
Blepharoptosis Associated With the Wearing of Hard Contact Lenses in Keratoconic Eyes.
Cureus
November 2024
Ophthalmology, International University of Health and Welfare, Chiba, JPN.
Keratoconus is a condition that causes progressive thinning and anterior protrusion of the cornea. Because of its irregular astigmatism, mild to moderate keratoconus is corrected with hard contact lenses (HCLs), but blepharoptosis due to the long-term wearing of HCLs is often a problem. In this study, we investigated blepharoptosis in HCL wearers with keratoconus.
View Article and Find Full Text PDFCelebrating 30 years of an ongoing annual international contact lens prescribing survey (1996-2025).
Cont Lens Anterior Eye
December 2024
Optometry and Vision Science, Queensland University of Technology, Kelvin Grove, Queensland, Australia. Electronic address:
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!