AI Article Synopsis
- A study compared the effects of transcranial direct current stimulation on two areas of the brain (premotor and primary motor cortex) alongside constraint-induced movement therapy in stroke patients.
- Sixty stroke patients were divided into three groups: one receiving stimulation on the premotor cortex, another on the primary motor cortex, and a third with sham stimulation, all undergoing the same therapy.
- Results showed that the group with premotor cortex stimulation had the most significant improvements in functional independence and other measures, suggesting the premotor area plays a key role in motor recovery for patients with severe disabilities early after a stroke.
Article Abstract
We compared the effects of transcranial direct current stimulation at different cortical sites (premotor and motor primary cortex) combined with constraint-induced movement therapy for treatment of stroke patients. Sixty patients were randomly distributed into 3 groups: Group A, anodal stimulation on premotor cortex and constraint-induced movement therapy; Group B, anodal stimulation on primary motor cortex and constraint-induced movement therapy; Group C, sham stimulation and constraint-induced movement therapy. Evaluations involved analysis of functional independence, motor recovery, spasticity, gross motor function, and muscle strength. A significant improvement in primary outcome (functional independence) after treatment in the premotor group followed by primary motor group and sham group was observed. The same pattern of improvement was highlighted among all secondary outcome measures regarding the superior performance of the premotor group over primary motor and sham groups. Premotor cortex can contribute to motor function in patients with severe functional disabilities in early stages of stroke. This study was registered in ClinicalTrials.gov database (NCT 02628561).
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303863 | PMC |
| http://dx.doi.org/10.1155/2017/6842549 | DOI Listing |
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