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Assessment of Cognitive Functions in Multimorbid Patients in Lithuanian Primary Care Settings: A Cross-Sectional Study Using MMSE and LT-GPCOG.
Medicina (Kaunas)
January 2025
Faculty of Nursing, Lithuanian University of Health Sciences, LT-44307 Kaunas, Lithuania.
: The aging population has led to a rise in cognitive impairments, including dementia, often associated with multimorbidity. Early diagnosis of cognitive decline is crucial, especially in primary care, where time constraints and the limitations of diagnostic tools may hinder accurate detection. This study aims to assess the cognitive functions of multimorbid patients using the Mini-Mental State Examination (MMSE) and the Lithuanian version of the General Practitioner Assessment of Cognition (LT-GPCOG).
View Article and Find Full Text PDFProgressive systemic inflammation precedes decompensation in compensated cirrhosis.
JHEP Rep
February 2025
Department of Gastroenterology and Hepatology, Hospital Universitario Ramón y Cajal, Instituto Ramon y Cajal de Investigación Sanitaria (IRYCIS), Universidad de Alcalá, Madrid, Spain.
Background & Aims: Systemic inflammation is a driver of decompensation in cirrhosis with unclear relevance in the compensated stage. We evaluated inflammation and bacterial translocation markers in compensated cirrhosis and their dynamics in relation to the first decompensation.
Methods: This study is nested within the PREDESCI trial, which investigated non-selective beta-blockers for preventing decompensation in compensated cirrhosis and clinically significant portal hypertension (CSPH: hepatic venous pressure gradient ≥10 mmHg).
Long-term Impact of Carotid Endarterectomy on Choroidal and Choriocapillaris Perfusion: The INFLATE Study.
Ophthalmol Sci
November 2024
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.
Purpose: When performed for clinically significant carotid artery stenosis (CAS), the long-term impact of carotid endarterectomy (CEA) on choroidal and choriocapillaris (CC) circulation was studied using swept-source OCT angiography.
Design: Prospective observational study.
Participants: Patients with clinically significant CAS undergoing unilateral CEA.
Nationwide study on multimorbidity prevalence: 7.64 million primary healthcare users in Portugal with multiple chronic conditions.
Public Health
January 2025
Faculty of Health Sciences, University of Beira Interior, Covilhã, Portugal; Family Health Unit Beira Ria, Gafanha da Nazaré, Portugal; CINTESIS@RISE, MEDCIDS, Faculty of Medicine of the University of Porto, Porto, Portugal. Electronic address:
Objectives: The goal of this study was to explore the prevalence of multimorbidity, its geographic variation, and changes from 2022 to 2024 in Portugal.
Study Design: Information regarding the chronic health conditions active in the primary healthcare patients' health problems lists on the electronic health records are derived from the digital platform Identity Card of Primary Healthcare (Bilhete de Identidade dos Cuidados de Saúde Primários, BI CSP) data for the period of 2022 and 2024.
Methods: BI CSP nationwide data from May 2024 of the 10,366,861 registered users in Portuguese primary healthcare were used to determine the prevalence of multimorbidity (presence of 2 or more chronic health conditions) and analize differences to 2022.
Meteorin-like protein plasma levels are associated with worse outcomes in de novo heart failure.
Eur J Clin Invest
January 2025
Cellular and Molecular Cardiology Research Unit, IDIS, Complexo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, Spain.
Background And Aims: Meteorin-like protein (Metrnl) has been recently suggested as a new adipokine with protective cardiovascular effects. Its circulating levels in patients seem to be associated with heart failure (HF), although with contradictory results. Our aim was to ascertain whether this adipokine could estimate the prognosis of HF in de novo HF (DNHF) patients.
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