AI Article Synopsis
- A new microscopy technique called S2MIM enhances regular microscopes by combining superresolution and multiplexing to achieve improved imaging.
- This method builds on earlier techniques, specifically the SMIM approach, and transforms standard microscopes into superresolved holographic instruments.
- The effectiveness of S2MIM was tested using an Olympus BX-60 microscope with specific resolution test targets, demonstrating its capability for high-resolution imaging.
Article Abstract
Superresolution capability by angular and time multiplexing is implemented onto a regular microscope. The technique, named superresolved spatially multiplexed interferometric microscopy (S2MIM), follows our previously reported SMIM technique [Opt. Express22, 14929 (2014)OPEXFF1094-408710.1364/OE.22.014929, J. Biomed. Opt.21, 106007 (2016)JBOPFO1083-366810.1117/1.JBO.21.10.106007] improved with superresolved imaging. All together, S2MIM updates a commercially available non-holographic microscope into a superresolved holographic one. Validation is presented for an Olympus BX-60 upright microscope with resolution test targets.
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| http://dx.doi.org/10.1364/OL.42.000927 | DOI Listing |
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