Un(MaSC)ing Stem Cell Dynamics in Mammary Branching Morphogenesis.

Dev Cell

Translational Research Program, Public Health Sciences and Human Biology Divisions, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. Electronic address:

Published: February 2017

The properties of stem cells that participate in mammary gland branching morphogenesis remain contested. Reporting in Nature, Scheele et al. (2017) establish a model for post-pubertal mammary branching morphogenesis in which position-dependent, lineage-restricted stem cells undergo cell mixing in order to contribute to long-term growth.

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http://dx.doi.org/10.1016/j.devcel.2017.02.014DOI Listing

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