The perceived color of a uniform image patch depends not only on the spectral content of the light that reaches the eye but also on its context. One of the most extensively studied forms of context dependence is a simultaneous contrast display: a center-surround display containing a homogeneous target embedded in a homogenous surround. A number of models have been proposed to account for the chromatic transformations of targets induced by such surrounds, but they were typically derived in the restricted context of experiments using achromatic targets with surrounds that varied along the cardinal axes of color space. There is currently no theoretical consensus that predicts the target color that produces the largest perceived color difference for two arbitrarily chosen surround colors, or what surround would give the largest color induction for an arbitrarily chosen target. Here, we present a method for assessing simultaneous contrast that avoids some of the methodological issues that arise with nulling and matching experiments and diminishes the contribution of temporal adaption. Observers were presented with pairs of center-surround patterns and ordered them from largest to smallest in perceived dissimilarity. We find that the perceived difference for two arbitrarily chosen surrounds is largest when the target falls on the line connecting the two surrounds in color space. We also find that the magnitude of induction is larger for larger differences between chromatic targets and surrounds of the same hue. Our results are consistent with the direction law (Ekroll & Faul, 2012b), and with a generalization of Kirschmann's fourth law, even for viewing conditions that do not favor temporal adaptation.
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http://dx.doi.org/10.1167/17.2.13 | DOI Listing |
The concentrations of individual proteins vary between cells, both developmentally and stochastically. The functional consequences of this variation remain largely unexplored due to limited experimental tools to manipulate the relationship of protein concentration to activity. Here, we introduce a genetically encoded tool based on a tunable amyloid that enables precise control of protein concentration thresholds in cells.
View Article and Find Full Text PDFSci Rep
January 2025
Biomedical Engineering, University of Calgary, Calgary, AB, Canada.
Humans sometimes synchronize their steps to mechanical oscillations in the environment (e.g., when walking on a swaying bridge or with a wearable robot).
View Article and Find Full Text PDFSensors (Basel)
December 2024
The State Key Laboratory for the Safety, Long-Life, Health Operation and Maintenance of Long-Span Bridges, Jiangsu Provincial Institute of Traffic Science (JSTI Group), Nanjing 210098, China.
The strain data acquired from structural health monitoring (SHM) systems of large-span bridges are often contaminated by a mixture of temperature-induced and vehicle-induced strain components, thereby complicating the assessment of bridge health. Existing approaches for isolating temperature-induced strains predominantly rely on statistical temperature-strain models, which can be significantly influenced by arbitrarily chosen parameters, thereby undermining the accuracy of the results. Additionally, signal processing techniques, including empirical mode decomposition (EMD) and others, frequently yield unstable outcomes when confronted with nonlinear strain signals.
View Article and Find Full Text PDFbioRxiv
December 2024
Department of Molecular Biosciences and Center for Genomics, University of Kansas, 1200 Sunnyside Avenue, Lawrence, KS 66045, USA.
Work in many systems has shown large-scale changes in gene expression during aging. However, many studies employ just two, arbitrarily-chosen timepoints at which to measure expression, and can only observe an increase or a decrease in expression between "young" and "old" animals, failing to capture any dynamic, non-linear changes that occur throughout the aging process. We used RNA sequencing to measure expression in male head tissue at 15 timepoints through the lifespan of an inbred strain.
View Article and Find Full Text PDFJ Cachexia Sarcopenia Muscle
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Department of Epidemiology of Aging, Research Institute, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.
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