[Advances of Diagnostic Biomarkers on Acute Graft Versus Host Disease -Review].

Zhongguo Shi Yan Xue Ye Xue Za Zhi

Department of Hematology, Chinese PLA General Hospital, Medical College of Chinese PLA, Beijing 100853, China.

Published: February 2017

Acute graft-versus-host disease (aGVHD) is one of the main complications after allogeneic hematopoietic stem cell transplantation (HCT), resulting in considerable morbidity and mortality. Diagnosis of aGVHD is typically based on clinical presentation and confirmed by biopsy. In recent years, aGVHD researches have been focused on diagnostic biomarkers, and several microRNAs, cytokines and immunoregulated cells have been dicovered currently. This review summarizes the advances on aGVHD biomarkers.

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Source
http://dx.doi.org/10.7534/j.issn.1009-2137.2017.01.051DOI Listing

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