We report a case of a Caucasian female who developed active polypoidal choroidal vasculopathy (PCV) at the edge of a stable choroidal nevus and was successfully treated with verteporfin photodynamic therapy. No active polyp was detectable on indocyanine green angiography 2 years after treatment, and good vision was maintained. Indocyanine green angiography is a useful investigation to diagnose PCV and may be underutilized. Unlike treatment of choroidal neovascularization secondary to choroidal nevus, management of PCV secondary to nevus may not require intravitreal anti-vascular endothelial growth factor therapy. Photodynamic monotherapy may be an effective treatment of secondary PCV.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317340 | PMC |
http://dx.doi.org/10.2147/IMCRJ.S107648 | DOI Listing |
Am J Case Rep
December 2024
Department of Oncology-Ophthalmology, Curie Institute, Paris, France.
BACKGROUND Optic disc melanocytoma (magnocellular nevus of the optic disc) is a benign congenital pigmented tumor, usually unilateral, asymptomatic, and mostly discovered in routine examinations in adult patients; however, it is associated with choroidal neovascularization. It can be difficult to differentiate it from juxta-papillary choroidal melanoma. Aflibercept is a monoclonal antibody targeting vascular endothelial growth factor A (anti-VEGF-A).
View Article and Find Full Text PDFUltrasonics
March 2025
Department of Radiology, Mayo Clinic, Rochester, MN, USA; Department of Ophthalmology, Mayo Clinic, Rochester, MN, USA. Electronic address:
Objective: This research aims to develop a noninvasive ultrasound vibro-elastography technique for assessing ocular lesions including intraocular melanoma and nevus lesions.
Method: Wave speed (WS) was noninvasively measured in the lesions at three different frequencies (i.e.
Sci Rep
November 2024
Department of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Pathologie (Heidelb)
October 2024
Klinik und Poliklinik für Augenheilkunde, Universitätsmedizin Rostock, Rostock, Deutschland.
We report on a 19-year-old patient with Sturge-Weber syndrome (SWS), accompanied by a Naevus flammeus, secondary glaucoma, and glaucomatous optic atrophy of the right eye. The painful and blind eye was enucleated. Histopathological analysis revealed a circumscribed choroidal hemangioma around the optic nerve and a smaller extrascleral hemangioma.
View Article and Find Full Text PDFOphthalmol Sci
August 2024
Division of Eye and Vision, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Purpose: To develop and validate a deep learning algorithm capable of differentiating small choroidal melanomas from nevi.
Design: Retrospective multicenter cohort study.
Participants: A total of 802 images from 688 patients diagnosed with choroidal nevi or melanoma.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!