AI Article Synopsis
- Recent research indicates that childhood abuse, neuroticism, and adult stress interact in influencing depressive symptoms in adults.
- A study with 413 participants used various self-report scales to assess the impact of these factors, finding that childhood abuse and neuroticism directly worsen depression and alter perceptions of life events.
- The findings suggest neuroticism plays a key mediating role between childhood abuse and depressive symptoms, although the study's design limits clear causal conclusions due to potential recall bias.
Article Abstract
Background: Recent studies have suggested that the interactions among several factors affect the onset, progression, and prognosis of major depressive disorder. This study investigated how childhood abuse, neuroticism, and adult stressful life events interact with one another and affect depressive symptoms in the general adult population.
Subjects And Methods: A total of 413 participants from the nonclinical general adult population completed the Patient Health Questionnaire-9, the Child Abuse and Trauma Scale, the neuroticism subscale of the shortened Eysenck Personality Questionnaire - Revised, and the Life Experiences Survey, which are self-report scales. Structural equation modeling (Mplus version 7.3) and single and multiple regressions were used to analyze the data.
Results: Childhood abuse, neuroticism, and negative evaluation of life events increased the severity of the depressive symptoms directly. Childhood abuse also indirectly increased the negative appraisal of life events and the severity of the depressive symptoms through enhanced neuroticism in the structural equation modeling.
Limitations: There was recall bias in this study. The causal relationship was not clear because this study was conducted using a cross-sectional design.
Conclusion: This study suggested that neuroticism is the mediating factor for the two effects of childhood abuse on adulthood depressive symptoms and negative evaluation of life events. Childhood abuse directly and indirectly predicted the severity of depressive symptoms.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317351 | PMC |
| http://dx.doi.org/10.2147/NDT.S128557 | DOI Listing |
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