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| http://dx.doi.org/10.1073/pnas.1700736114 | DOI Listing |
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Role of polymer graft stiffness in electrostatic-driven self-assembly of nanoparticles in solutions.
Phys Chem Chem Phys
January 2025
Department of Chemical Engineering, Indian Institute of Technology Gandhinagar, India.
Self-assembly of nanoparticles (NPs) in solution has garnered tremendous attention among researchers because of their electrical, chemical, and optoelectronic properties at the macroscale with potential applications in bio-imaging, bio-medicine, and therapeutics. Control of size, shape, and composition at the nanoscale is important in tuning the material's bulk properties. The grafting of NPs with polymers enables us to tune such bulk material properties at the nano level by controlling their assemblies, especially in solutions.
View Article and Find Full Text PDFOrigin of the Temperature Dependence of Gate-Induced Drain Leakage-Assisted Erase in Three-Dimensional nand Flash Memories.
Micromachines (Basel)
December 2024
Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, 20133 Milan, Italy.
Through detailed experimental and modeling activities, this paper investigates the origin of the temperature dependence of the Erase operation in 3D nand flash arrays. First of all, experimental data collected down to the cryogenic regime on both charge-trap and floating-gate arrays are provided to demonstrate that the reduction in temperature makes cells harder to Erase irrespective of the nature of their storage layer. This evidence is then attributed to the weakening, with the decrease in temperature, of the gate-induced drain leakage (GIDL) current exploited to set the electrostatic potential of the body of the nand strings during Erase.
View Article and Find Full Text PDFHalf-integer topological defects paired via string micelles in polar liquids.
PNAS Nexus
December 2024
Department of Mechanical and Energy Engineering, Southern University of Science and Technology, Shenzhen 518055, China.
Ferroelectric nematic (N) liquid crystals present a compelling platform for exploring topological defects in polar fields, while their structural properties can be significantly altered by ionic doping. In this study, we demonstrate that doping the ferroelectric nematic material RM734 with cationic polymers enables the formation of polymeric micelles that connect pairs of half-integer topological defects. Polarizing optical microscopy reveals that these string defects exhibit butterfly textures, featured with a 2D polarization field divided by Néel-type kink walls into domains exhibiting either uniform polarization or negative splay and bend deformations.
View Article and Find Full Text PDFThe landscape of intrinsically disordered proteins in Leishmania parasite: Implications for drug discovery.
Int J Biol Macromol
December 2024
Department of Biotechnology, National Institute of Technology-Warangal, Warangal 506004, Telangana, India. Electronic address:
Proteins that lack three-dimensional structures are known as Intrinsically disordered proteins (IDPs). In this study, we aimed to identify intrinsically disordered proteins in the Leishmania donovani proteome using various predictors that can identify IDPs based on amino acid residues and charge hydropathy. Top identified IDPs are analyzed using STRING, PSP-Hunter, Deep Loc-2.
View Article and Find Full Text PDFBuild-a-Bio-Strip: An Online Platform for Rapid Toxicity Assessment in Chemical Synthesis.
J Chem Inf Model
November 2024
Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow 119991, Russia.
The increasing need to understand and control the environmental impact of chemical processes has revealed the challenge in efficient evaluation of toxicity of the vast number of chemical compounds and their varying effects on biological systems. In this study, we introduce "Build-a-bio-Strip", a novel online service designed to carry out a quick initial analysis of the toxic impact of chemical processes. This platform enables users to automatically generate toxicity characteristics of chemical reactions using their own data on cytotoxicity or median lethal doses of the substances involved or computational predictions based on SMILES strings.
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