Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2217/bmm-2017-0019 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Novel Non-Invasive Diagnosis of Bladder Cancer in Urine Based on Multifunctional Nanoparticles.
Front Cell Dev Biol
January 2022
Department of Urology, Changhai Hospital, Naval Medical University, Shanghai, China.
Tumor cells were reported to have perpetual negative surface charges due to elevated glycolysis, and multifunctional nanoprobes (FeO@SiO mNPs) could attach onto tumor cells opposite surface charges. We thus evaluated whether mixing mNPs with urine could improve the sensitivity of urine cytology test (UCT). We developed a novel UCT method by mixing urine with mNPs (Nano-cytology) to harvest more tumor cells during UCT procedures.
View Article and Find Full Text PDFNanocytology as a potential biomarker for cancer.
Biomark Med
March 2017
Department of Pathology & Laboratory Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90095, USA.
Higher Order Chromatin Modulator Cohesin SA1 Is an Early Biomarker for Colon Carcinogenesis: Race-Specific Implications.
Cancer Prev Res (Phila)
November 2016
Department of Medicine, Boston University Medical Center, Boston, Massachusetts.
Alterations in high order chromatin, with concomitant modulation in gene expression, are one of the earliest events in the development of colorectal cancer. Cohesins are a family of proteins that modulate high-order chromatin, although the role in colorectal cancer remains incompletely understood. We, therefore, assessed the role of cohesin SA1 in colorectal cancer biology and as a biomarker focusing in particular on the increased incidence/mortality of colorectal cancer among African-Americans.
View Article and Find Full Text PDFHigh-speed spectral nanocytology for early cancer screening.
J Biomed Opt
November 2013
Northwestern University, Department of Biomedical Engineering, 2145 Sheridan Road, Evanston, Illinois 60208.
High-throughput partial wave spectroscopy (HTPWS) is introduced as a high-speed spectral nanocytology technique that utilizes the field effect of carcinogenesis to perform minimally invasive cancer screening on at-risk populations. HTPWS uses fully automated hardware and an acousto-optic tunable filter to scan slides at low magnification, to select cells, and to rapidly acquire spectra at each spatial pixel in a cell between 450 and 700 nm, completing measurements of 30 cells in 40 min. Statistical quantitative analysis on the size and density of intracellular nanostructures extracted from the spectra at each pixel in a cell yields the diagnostic biomarker, disorder strength (Ld).
View Article and Find Full Text PDFNanoscale markers of esophageal field carcinogenesis: potential implications for esophageal cancer screening.
Endoscopy
December 2013
Center for Endoscopic Research and Therapeutics, Section of Gastroenterology, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois, USA.
Background And Study Aims: Esophageal adenocarcinoma (EAC) has a dismal prognosis unless treated early or prevented at the precursor stage of Barrett's esophagus-associated dysplasia. However, some patients with cancer or dysplastic Barrett's esophagus (DBE) may not be captured by current screening and surveillance programs. Additional screening techniques are needed to determine who would benefit from endoscopic screening or surveillance.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!