Background: Cancer is one of the most common causes of human mortality, with about 14 million new cases and 8.2 million deaths reported in in 2012. Early diagnosis of cancer through screening allows interventions to reduce mortality. Fractal analysis of medical images may be useful for this purpose. Materials and Methods: In this study, we examined magnetic resonance (MR) images of healthy livers and livers containing metastases from colorectal cancer. The fractal dimension and the Hurst exponent were chosen as diagnostic features for tomographic imaging using Image J software package for image processings FracLac for applied for fractal analysis with a 120x150 pixel area. Calculations of the fractal dimensions of pathological and healthy tissue samples were performed using the box-counting method. Results: In pathological cases (foci formation), the Hurst exponent was less than 0.5 (the region of unstable statistical characteristics). For healthy tissue, the Hurst index is greater than 0.5 (the zone of stable characteristics). Conclusions: The study indicated the possibility of employing fractal rapid analysis for the detection of focal lesions of the liver. The Hurst exponent can be used as an important diagnostic characteristic for analysis of medical images.
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http://dx.doi.org/10.22034/APJCP.2017.18.1.51 | DOI Listing |
Med Image Anal
November 2024
Department of Radiology and Nuclear Medicine, St. Olav's University Hospital, Trondheim, Norway; Department of Circulation and Medical Imaging, NTNU - Norwegian University of Science and Technology, Trondheim, Norway.
In medical image analysis, the utilization of biophysical models for signal analysis offers valuable insights into the underlying tissue types and microstructural processes. In diffusion-weighted magnetic resonance imaging (DWI), a major challenge lies in accurately estimating model parameters from the acquired data due to the inherently low signal-to-noise ratio (SNR) of the signal measurements and the complexity of solving the ill-posed inverse problem. Conventional model fitting approaches treat individual voxels as independent.
View Article and Find Full Text PDFSci Rep
December 2024
School of Civil Engineering and Architecture, Anhui University of Science and Technology, Huainan, 232001, Anhui, China.
The mechanical behavior and fracture mechanisms of deep fractured rocks under explosive dynamic loads are critical for understanding rock instability in engineering applications such as blasting operations. This study aims to investigate how the presence of pre-existing cracks and different stress states affect the mechanical properties and fracture patterns of rock-like specimens under dynamic loading conditions. We utilized a Split Hopkinson Pressure Bar (SHPB) with an active confining pressure loading device to conduct impact compression tests on rock-like specimens containing pre-existing cracks.
View Article and Find Full Text PDFNat Commun
December 2024
Department of Chemical Engineering, The University of Melbourne, Parkville, Victoria, Australia.
Colloidal properties of nanoparticles are intricately linked to their morphology. Traditionally, achieving high-concentration dispersions of two-dimensional (2D) nanosheets has proven challenging as they tend to agglomerate or re-stack under increased surface contact and Van der Waals attraction. Here, we unveil an excluded volume effect enabled by 2D morphology, which can be coupled with electrostatic repulsion to synthesize high-concentration aqueous graphene dispersions.
View Article and Find Full Text PDFVegetation restoration can be effective in containing gully head advance. However, the effect of vegetation restoration type on soil aggregate stability and erosion resistance at the head of the gully is unclear. In this study, five types of vegetation restoration-Pinus tabulaeformis (PT), Prunus sibirica (PS), Caragana korshinskii (CKS), Hippophae rhamnoides (HR), and natural grassland (NG, the dominant species is Leymus chinensis)-in the gully head were studied.
View Article and Find Full Text PDFComput Methods Programs Biomed
December 2024
Department of Industrial Engineering, Faculty of Engineering, King Abdulaziz University, Jeddah 21589, Saudi Arabia. Electronic address:
Background And Objective: Cancer's complex and multifaceted nature makes it challenging to identify unique molecular and pathophysiological signatures, thereby hindering the development of effective therapies. This paper presents a novel fractal-fractional cancer model to study the complex interplay among stem cells, effectors cells, and tumor cells in the presence and absence of chemotherapy. The cancer model with effective treatment through chemotherapy drugs is considered and discussed in detail.
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