Objective: Liver surgery is considered a curative treatment for hepatocellular carcinoma (HCC) but the importance of resection margin width remains controversial. The aim of this study is to clarify the role of 5-10 mm surgical margin width on post-operative recurrence and overall survival after resection.
Patients And Methods: We analyzed recurrence rate and overall survival rate of 72 patients who underwent curative hepatic resection for HCC smaller than 5 cm with 5-10 mm surgical margin width between January 2005 and December 2014.
Results: The mean follow-up period was 36 months. Among the seventy-two patients, thirty-one (31/72; 43%) developed recurrence but only eleven (11/31; 15.3%) along the resection margin. The disease-free survival was 77.2%, 50%, 41.4% at 1, 3 and 5 years respectively, and the overall survival was 89.9%, 78.8%, 60% at 1, 3 and 5 years respectively.
Conclusions: 5-10 mm surgical resection margin for HCC smaller than 5 cm seems to be safe as a wider surgical margin because does not increase the risk of marginal recurrence and does not decrease overall survival rate. Further prospective and randomized studies are required to definitively clarify the importance of surgical margin width in hepatic resection for HCC.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Expansion of perceived passable width in older adults.
Hum Mov Sci
January 2025
Faculty of Humanities and Social Sciences (Psychology), Kumamoto University, 2-40-1 Kurokami, Kumamoto 860-8555, Japan.
Humans can perceive whether an aperture is passable; this ability is known as passable width perception. Previous studies have shown that passable width in older adults is larger when walking and suggested the effect of larger body sway in older adults while walking on passable width expansion. However, no studies have directly investigated this.
View Article and Find Full Text PDFAim: To compare the effect of the shape of the healing abutment, concave or straight, on the dimensions of the soft tissue after healing.
Materials And Methods: Patients needing implant therapy in the posterior area were treated with a 1-stage surgery protocol; concave (CONC) or straight (STR) healing abutments were randomly assigned after implant installation. Before surgery, a CBCT and an intra-oral scan were obtained (IOS#0); IOS#1 was taken after soft tissue healing.
Narrow Versus Standard Diameter Implants for Supporting Single Crown Restorations in the Posterior Jaw: A Randomised Controlled Trial.
Int Dent J
January 2025
Department of Dental Services, Emirates Health Services, Dubai, United Arab Emirates.
Objectives: The aim of this randomised controlled trial was to assess clinical, radiographic and patient reported outcomes of narrow versus standard diameter titanium zirconium (TiZr) implants supporting single crown restorations in posterior sites with limited bone width.
Materials And Methods: Participants requiring replacement of single missing posterior teeth with implant-supported crowns were randomly allocated into 2 treatment groups: narrow (3.3 mm) or standard (4.
Imaging Retrospective Study Regarding the Variability of the Osseous Landmarks for IAN Block.
J Clin Med
January 2025
Department of Anesthesiology and Oral Surgery, Multidisciplinary Center for Research, Evaluation, Diagnosis and Therapies in Oral Medicine, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.
: The aim of this study is to identify the most accurate and consistent landmarks for determining the precise location of the mandibular foramen (MF) and the mandibular ramus, suggesting appropriate adjustments to anesthesia techniques based on these variations in order to improve the success rate of the inferior alveolar nerve (IAN) block. : CT scans of the mandibles from 100 patients were analyzed to measure the distance between the MF and various landmarks, including the sigmoid notch, gonion, posterior and anterior margins of the ramus, temporal crest, and the mandibular ramus height from the condyle to the gonion. The width of the mandibular ramus was also assessed, with correlations made to age and gender.
View Article and Find Full Text PDFComparative Analysis of Automated and Handheld Breast Ultrasound Findings for Small (≤1 cm) Breast Cancers Based on BI-RADS Category.
Diagnostics (Basel)
January 2025
Department of Radiology, Inje University Haeundae Paik Hospital, Busan 48108, Republic of Korea.
: This study aimed to compare ultrasound (US) findings between automated and handheld breast ultrasound (ABUS and HHUS, respectively) in small breast cancers, based on the breast imaging reporting and data system (BI-RADS) category. : We included 51 women (mean age: 52 years; range: 39-66 years) with breast cancer (invasive or DCIS), all of whom underwent both ABUS and HHUS. Patients with tumors measuring ≤1 cm on either modality were enrolled.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!