Laparoscopy vs. Robotic Surgery for Endometriosis (LAROSE): a multicenter, randomized, controlled trial.

Objective: To determine whether the use of the robot for surgical treatment of endometriosis is better than traditional laparoscopy in terms of operative length, perioperative parameters, and quality of life outcomes.

Design: Multicenter, randomized clinical trial.

Setting: University teaching hospitals.

Patient(s): Women aged >18 years with suspected endometriosis who elected to undergo surgical management.

Intervention(s): Randomization to conventional or robot-assisted laparoscopic removal of endometriosis.

Main Outcome Measure(s): The primary outcome measured was operative time. Secondary outcomes were perioperative complications and quality of life.

Result(s): The mean operative time for robotic vs. laparoscopic surgery for endometriosis was 106.6 ± 48.4 minutes vs. 101.6 ± 63.2 minutes. There were no differences in blood loss, intraoperative or postoperative complications, or rates of conversion to laparotomy in the two arms. Both groups reported significant improvement on condition-specific quality of life outcomes at 6 weeks and 6 months.

Conclusion(s): There were no differences in perioperative outcomes between robotic and conventional laparoscopy.

Clinical Trial Registration Number: NCT01556204.