Resistance to EGFR kinase inhibitors appears to be invariable in the treatment of non-small cell lung cancer. Several mechanisms have been described. Here, we report the first case of histologic transformation of EGFR mutant lung adenocarcinoma without prior exposure to EGFR inhibition.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330183 | PMC |
| http://dx.doi.org/10.1016/j.lungcan.2017.01.005 | DOI Listing |
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