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Purpose: Results of a study of stress and negative affect levels in postgraduate year 1 (PGY1) and postgraduate year 2 (PGY2) pharmacy residents are presented.
Methods: A cross-sectional approach was used. Pharmacy residency program directors received e-mailed invitation letters requesting that they ask their residents to participate in an online survey in 2011. The main study outcomes included evaluation of resident scores on the 10-item Perceived Stress Scale (PSS10) and the Multiple Affect Adjective Checklist-Revised (MAACL-R) anxiety, depression, hostility, and dysphoria subscales.
Results: Of the 524 pharmacy residents included in the study, 75.4% were female, 41.2% were under 26 years of age, and 41% reported working more than 60 hours per week. There were no significant differences between PGY1 and PGY2 residents in stress levels, as assessed with the PSS10 (mean ± S.D. score, 19.05 ± 5.96 versus 19.09 ± 5.77). MAACL-R scores for hostility were, on average, higher among PGY2 residents (mean ± S.D., 50.83 ± 10.02) than among PGY1 residents (48.62 ± 8.96), while there were no significant differences in anxiety, depression, and dysphoria levels. Relative to residents who worked 60 or fewer hours per week, those who worked more than 60 hours had higher perceived stress levels as well as higher depression, hostility, and dysphoria scores.
Conclusion: Pharmacy residents exhibited high levels of perceived stress, especially those who worked more than 60 hours per week. Perceived stress was highly correlated to negative affect levels.
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http://dx.doi.org/10.2146/ajhp150763 | DOI Listing |
Australas J Ageing
March 2025
Faculty of Health, Medicine and Behavioural Sciences, School of Pharmacy and Pharmaceutical Sciences, The University of Queensland, Dutton Park Campus, Woolloongabba, Queensland, Australia.
Objectives: Accumulating evidence about psychotropic medication-related adverse events has had minimal apparent impact on overall rates of psychotropic medication use across Australian residential aged care facilities (RACFs). Australia's new Clinical Practice Guidelines for the Appropriate Use of Psychotropic Medications in People Living with Dementia and in Residential Aged Care were released in April 2023. This study aimed to identify contextual factors to inform strategies to implement the new Guidelines in Australian RACFs.
View Article and Find Full Text PDFJ Int Med Res
March 2025
Department of Science and Education, Xilingol League Central Hospital, Xilin Hot, Inner Mongolia, P.R. China.
This article presents a case report of a rare instance of hepatic cystic echinococcosis (Type II). The patient is a young female who has resided in the Inner Mongolia region of China for an extended period and has a clear history of contact with dogs and sheep. She presented with recurrent upper abdominal pain accompanied by jaundice of skin and sclera for 2 months.
View Article and Find Full Text PDFInfect Control Hosp Epidemiol
March 2025
Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
Objective: To better understand clinicians' rationale for ordering testing for infection (CDI) for patients receiving laxatives and the impact of the implementation of a clinical decision support (CDS) intervention.
Design: A mixed-methods, case series was performed from March 2, 2017 to December 31, 2018.
Setting: Yale New Haven Hospital, a 1,541 bed tertiary academic medical center.
Front Pharmacol
February 2025
James L. Winkle College of Pharmacy, University of Cincinnati, Cincinnati, OH, United States.
Purpose: Vancomycin is an essential antibiotic for the treatment of severe gram-positive bacterial infections, including methicillin-resistant (MRSA). In critically ill patients, particularly children, attaining the appropriate dosage is crucial to avert drug resistance and ensure therapeutic efficacy. This study sought to investigate the pharmacokinetics of vancomycin in critically ill Asian pediatric patients and evaluate the influence of extracorporeal membrane oxygenation (ECMO) and disease severity on vancomycin clearance.
View Article and Find Full Text PDFDiagnostics (Basel)
February 2025
Vietnam Association for Fluid Mechanics and Water Resources Engineering Department, University of Science and Technology, The University of Danang, Danang 550000, Vietnam.
In the study of coronary artery disease, the mechanisms underlying atherosclerosis initiation and progression or regression remain incompletely understood. Our research conceptualized the cardiovascular system as an integrated network of pumps and pipes, advocating for a paradigm shift from static imaging of coronary stenosis to dynamic assessments of coronary flow. Further review of fluid mechanics highlighted the water hammer phenomenon as a compelling analog for processes in coronary arteries.
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