Objective: This study aims to analyze the association between the incidence of tuberculosis and different socioeconomic indicators in a territory of intense transformation of the urban space.
Methods: This is an ecological study, whose analysis units were the neighborhoods of the city of Itaboraí, state of Rio de Janeiro, Brazil. The data have been analyzed by generalized linear models. The response variable was incidence of tuberculosis from 2006 to 2011. The independent variables were the socio-demographic indicators. The spatial distribution of tuberculosis was analyzed with the elaboration of thematic maps.
Results: The results have shown a significant association between the incidence of tuberculosis and variables that reflect different dimensions of living conditions, such as consumer goods, housing conditions and its surroundings, agglomeration of population, and income distribution.
Conclusions: The disproportionate incidence of tuberculosis in populations with worse living conditions highlights the persistence of socioeconomic determinants in the reproduction of the disease. Different municipal public sectors need to better articulate with local tuberculosis control programs to reduce the social burden of the disease.
Objetivo: Analisar a associação entre incidência de tuberculose e diferentes indicadores socioeconômicos em território em intensa transformação do espaço urbano.
MÉtodos: Estudo ecológico, cujas unidades de análise foram os bairros do município de Itaboraí, RJ. Os dados foram analisados por modelos lineares generalizados. A variável resposta foi incidência de tuberculose de 2006 a 2011. As variáveis independentes foram os indicadores sociodemográficos. A distribuição espacial da tuberculose foi analisada por meio da elaboração de mapas temáticos.
Resultados: Os resultados apontaram associação significativa entre a incidência de tuberculose e variáveis que refletem diferentes dimensões de condições de vida, como bens de consumo, condições de moradia e seu entorno, aglomeração populacional e distribuição de renda.
ConclusÕes: O acometimento desproporcional da tuberculose em grupos populacionais com piores condições de vida ressalta a persistência dos determinantes socioeconômicos na reprodução da doença. Faz-se necessária a melhor articulação de diferentes setores públicos municipais com o programa local de controle da tuberculose visando à redução da carga social da doença.
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http://dx.doi.org/10.1590/S1518-8787.2017051006533 | DOI Listing |
Clin Interv Aging
January 2025
Department of Infectious Diseases, Wenzhou Central Hospital, Wenzhou, People's Republic of China.
Objective: To understand the current status and analyse the factors influencing frailty in older adults patients with pulmonary tuberculosis.
Methods: This retrospective case-control study included 204 older adults patients with pulmonary tuberculosis. The enrolled patients were divided into a frailty group (n = 101) and a non-frailty group (n = 103).
Perspect Clin Res
August 2024
Centre for Digital Health, Artificial Intelligence, Research and Training, Basaweshwara Medical College and Hospital, Chitradurga, Karnataka, India.
Aim: The study aimed to determine the incidence of adverse drug reactions (ADRs) among newly diagnosed tuberculosis (TB) patients receiving daily drug regimen with fixed-dose combination treatment under the National Tuberculosis Elimination Program.
Materials And Methods: A community-based prospective cohort study was carried out in the Udupi district. Over 12 months, all newly diagnosed TB patients of either gender were included from 63 primary health centers and 6 community health centers, and ADRs were recorded by personal interviews.
Cureus
December 2024
Internal Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, THA.
Recent research suggests that tuberculosis (TB) may pose a potential risk factor for osteoporosis, although the available evidence remains limited. This study aimed to comprehensively assess osteoporosis risk in TB patients through systematic review and meta-analysis methodology. Two investigators independently conducted a literature search using the Medical Literature Analysis and Retrieval System Online (MEDLINE) and Excerpta Medica Database (EMBASE) databases up to April 2024.
View Article and Find Full Text PDFIJID Reg
March 2025
Department of Public Health Science, Indian Institute of Public Health Gandhinagar (IIPHG), Gandhinagar, India.
Tuberculosis (TB), caused by , remains a global health challenge, despite being preventable and curable. The global goal to end TB by 2030, with India targeting a 90% reduction in TB incidence by 2025, demands comprehensive interventions in prevention, early detection, treatment, and capacity building. This study analyzes the 2023 Global TB Reports, published articles, guidelines, and data to explore India's current TB landscape.
View Article and Find Full Text PDFTuberculosis (Edinb)
January 2025
Emory Vaccine Center, Emory University, Atlanta, GA, USA; Emory National Primate Research Center, Atlanta, GA, USA; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA. Electronic address:
Infection with HIV is associated with dysregulated CD4 T cell responses to Mycobacterium tuberculosis (Mtb) and increased risk of developing tuberculosis. Mtb-specific CD4 T cells in people with HIV have diminished Th1 cytokine production capacity, thus we utilized a flow cytometry-based assay to measure CD40L expression by Mtb-specific CD4 T cells in a cytokine-independent manner. We evaluated the frequency and phenotype of Mtb-specific CD4 responses in Kenyan adults with latent Mtb infection and found that the majority of Mtb-specific CD4 T cells expressed CD40L in the absence of IFN-γ, regardless of HIV infection status.
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