Nortriterpenoids from the stems and leaves of Schisandra viridis.

Fitoterapia

Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College of Huazhong University of Science and Technology, Hangkonglu 13, Wuhan 430030, People's Republic of China. Electronic address:

Published: April 2017

An extensive phytochemical study on the stems and leaves of Schisandra viridis A. C. Smith led to the isolation of two novel highly oxygenated schinortriterpenoids, pre-schisanartanin P (1) and wuweizidilactone Q (2), together with four known ones (3-6). Their structures with absolute configurations were established on the basis of comprehensive spectroscopic methods, including HRESIMS, 1D and 2D NMR analyses and ECD experiments. All isolates were evaluated for their in vitro cytotoxicities against HepG2, MCF-7 and HT-29 cancer cell lines, none of them showed significant activities.

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http://dx.doi.org/10.1016/j.fitote.2017.02.006DOI Listing

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