AI Article Synopsis
- The study examined how various drugs affect superoxide production in human neutrophils in a lab setting.
- Certain drugs like colchicine, g-strophanthin, propranolol, and fluphenazine were found to inhibit superoxide production, while levamisole and lithium stimulated it.
- Additionally, drugs such as chloramphenicol, hydrocortisone, and amphotericin B influenced superoxide production in a way that depended on their concentration.
Article Abstract
The in-vitro influence of drugs on the superoxide production of human neutrophils was investigated. The superoxide production is inhibited by colchicine, g-strophanthin, propranolol, fluphenazine and stimulated by levamisole and lithium. The superoxide production is inhibited or stimulated by chloramphenicol, hydrocortisone and amphotericin B in concentration dependent manner.
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