Gemcitabine induced cardiomyopathy: a case of multiple hit cardiotoxicity.

ESC Heart Fail

Program in Cardio-oncology, Department of Internal Medicine, Division of Cardiology, Beth Israel Deaconess Medical Center Harvard Medical School Boston MA USA.

Published: February 2017

Gemcitabine is a commonly used antineoplastic agent used to treat a variety of cancers with rarely reported cardiac side effects. We describe a case of a 67-year-old woman with follicular lymphoma who experienced a rarely reported side effect of gemcitabine: cardiomyopathy. This case highlights a multiple hit mechanism of myocyte damage that may occur following the use of multiple cardio-toxic agents despite their administration in doses not associated with cardiotoxicity.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292629PMC
http://dx.doi.org/10.1002/ehf2.12113DOI Listing

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