Carbon Nanostructures in Bone Tissue Engineering.

Open Orthop J

Reconstructive Surgery & Regenerative Medicine Group, Institute of Life Science (ILS), Swansea University Medical School, Swansea, SA2 8PP, United Kingdom; Welsh Centre for Burns & Plastic Surgery, Abertawe Bro Morgannwg University Health Board, Swansea, United Kingdom.

Published: December 2016

AI Article Synopsis

  • Advances in biocompatible materials for bone loss treatment are improving reconstructive options, but there are still drawbacks limiting their widespread use.
  • The review focuses on the use of carbon nanostructure composites in bone tissue engineering, highlighting their enhanced mechanical properties that can closely mimic natural bone.
  • It also summarizes the key chemical and biophysical characteristics of carbon nanostructures and their potential benefits for bone regeneration.

Article Abstract

Background: Recent advances in developing biocompatible materials for treating bone loss or defects have dramatically changed clinicians' reconstructive armory. Current clinically available reconstructive options have certain advantages, but also several drawbacks that prevent them from gaining universal acceptance. A wide range of synthetic and natural biomaterials is being used to develop tissue-engineered bone. Many of these materials are currently in the clinical trial stage.

Methods: A selective literature review was performed for carbon nanostructure composites in bone tissue engineering.

Results: Incorporation of carbon nanostructures significantly improves the mechanical properties of various biomaterials to mimic that of natural bone. Recently, carbon-modified biomaterials for bone tissue engineering have been extensively investigated to potentially revolutionize biomaterials for bone regeneration.

Conclusion: This review summarizes the chemical and biophysical properties of carbon nanostructures and discusses their functionality in bone tissue regeneration.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299584PMC
http://dx.doi.org/10.2174/1874325001610010877DOI Listing

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