Long-term outcomes of endolymphatic sac shunting with local steroids for Meniere's disease.

Objectives: To evaluate the long-term efficacy of endolymphatic sac shunt techniques with and without local steroid administration.

Study Design: Retrospective case series and patient survey.

Setting: Tertiary university hospital.

Patients: Meniere's disease (MD) patients that failed medical therapy and subsequently underwent an endolymphatic sac shunt procedure. All patients had definitive or probable MD and at least 18-months of follow-up.

Interventions: Three variations on endolymphatic sac decompression with shunt placement were performed: Group A received no local steroids, Group B received intratympanic dexamethasone prior to incision, and Group C received dexamethasone via both intratympanic injection and direct endolymphatic sac instillation.

Main Outcome Measure(s): Vertigo control, hearing results, and survey responses.

Results: Between 2002 and 2013, 124 patients with MD underwent endolymphatic sac decompression with shunt placement. 53 patients met inclusion criteria. Groups A, B, and C had 6 patients, 20 patients, and 27 patients, respectively. Mean follow-up was 56months. Vertigo control improved in 66%, 83%, and 93% of Groups A, B, and C. Functional level improved for Group B (-2.0) and Group C (-2.2) but was unchanged in Group A. Pure-tone average and speech discrimination scores changed by +22dB and -30%, +6dB and -13%, and +6dB and -5% in Groups A, B, and C. The long-term hearing results were significantly better with steroids (Groups B and C) according to the AAO-HNS 1995 criteria but did not meet significance on non-parametric testing.

Conclusions: Endolymphatic sac shunt procedures may benefit from steroid instillation at the time of shunt placement.