19.6% and 3.0% isolates of N. gonorrhoeae were found respectively to be resistant to penicillin and co-trimoxazole during the period of this study. Penicillin (procaine penicillin, 1.5 mega units + crystalline penicillin, 1.5 mega units) given intra- muscularly as a single injection was found to be slightly more effective compared to cotrimoxazole (Septran) 4 tablets twice daily X 2 days. Co-trimoxazole is a good alternative drug to penicillin and can be use in patients who are either allergic to penicillin or where penicillin has failed to cure the gonococcal infection. Cotrimoxazole was quite effective in the treatment of gonococc subacute prostatis.
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