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An IS element-driven antisense RNA attenuates the expression of serotype 2 fimbriae and the cytotoxicity of .
Emerg Microbes Infect
January 2025
Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, US 41 - UAR 2014 - PLBS, F-59000 Lille, France.
Insertion sequences (IS) represent mobile genetic elements that have been shown to be associated with bacterial evolution and adaptation due to their effects on genome plasticity. In , the causative agent of whooping cough, the numerous IS elements induce genomic rearrangements and contribute to the diversity of the global population. Previously, we have shown that the majority of IS-specific endogenous promoters induce the synthesis of alternative transcripts and thereby affect the transcriptional landscape of .
View Article and Find Full Text PDFCough-Induced Rib Fracture in a Postmenopausal Woman Without Clinical Evidence of Osteoporosis: A Case Report.
Cureus
December 2024
Department of Community Medicine, College of Medicine, Hawler Medical University, Erbil, IRQ.
Cough-induced rib fractures are rare conditions and are seldom reported in the medical literature. This case involves a 54-year-old postmenopausal woman who experienced a persistent dry cough lasting 16 days, which progressed to acute, localized chest pain in the right hemithorax. Symptoms started after an initial chest infection.
View Article and Find Full Text PDFPrevention of sufentanil-induced cough during induction of general anesthesia by low-dose esketamine.
BMC Anesthesiol
January 2025
Department of Anesthesiology, Air Force Medical Center, No.30 Fucheng Road, Haidian District, Beijing, 100142, China.
Background: Sufentanil is commonly used to induce general anaesthesia due to its rapid onset of action, strong analgesic effect, long-lasting effect, and stable haemodynamics; however, it often induces cough, increasing the risk of anaesthesia. This study aimed to investigate the preventive effect of low-dose esketamine on sufentanil-induced cough.
Methods: This randomised, double-blind, placebo-controlled clinical study was conducted at the Air Force Medical Center between September 2023 and May 2024.
pulmonary disease with organizing pneumonia: A case report and review of literature.
Respirol Case Rep
January 2025
Department of Respirology, Graduate School of Medicine Chiba University Chiba Japan.
, a rapidly growing non-tuberculous mycobacterium, rarely causes pulmonary diseases. A patient was admitted to our hospital with a fever and cough. Chest radiography revealed consolidation in the right middle lung.
View Article and Find Full Text PDFFarfarae Flos Mitigates Cigarette Smoking-Induced Lung Inflammation by Regulating the Lysophosphatidylcholine Biosynthesis and Tryptophan Metabolism.
Biomed Chromatogr
February 2025
Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan, China.
An increased risk of developing respiratory diseases has been linked to exposure to cigarette smoking (CS). The flower buds of Tussilago farfara L., also known as Farfarae Flos (FF), can be used for the treatment of cough, bronchitis, and asthmatic disorders in China.
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