Role of Academic Drug Discovery in the Quest for New CNS Therapeutics.

ACS Chem Neurosci

Johns Hopkins Drug Discovery, Departments of Neurology, Neuroscience, Psychiatry, Medicine, and Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, United States.

Published: March 2017

There was a greater than 50% decline in central nervous system (CNS) drug discovery and development programs by major pharmaceutical companies from 2009 to 2014. This decline was paralleled by a rise in the number of university led drug discovery centers, many in the CNS area, and a growth in the number of public-private drug discovery partnerships. Diverse operating models have emerged as the academic drug discovery centers adapt to this changing ecosystem.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795596PMC
http://dx.doi.org/10.1021/acschemneuro.7b00040DOI Listing

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