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Glucose-Sensitive Hydrogel Optical Fibers Functionalized with Phenylboronic Acid. | LitMetric
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Glucose-Sensitive Hydrogel Optical Fibers Functionalized with Phenylboronic Acid.

Ali K Yetisen Nan Jiang Afsoon Fallahi Yunuen Montelongo Guillermo U Ruiz-Esparza Ali Tamayol Yu Shrike Zhang Iram Mahmood Su-A Yang Ki Su Kim Haider Butt Ali Khademhosseini Seok-Hyun Yun

Adv Mater

Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, 65 Landsdowne Street, Cambridge, MA, 02139, USA.

Published: April 2017

Hydrogel optical fibers are utilized for continuous glucose sensing in real time. The hydrogel fibers consist of poly(acrylamide-co-poly(ethylene glycol) diacrylate) cores functionalized with phenylboronic acid. The complexation of the phenylboronic acid and cis-diol groups of glucose enables reversible changes of the hydrogel fiber diameter. The analyses of light propagation loss allow for quantitative glucose measurements within the physiological range.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921932PMC
http://dx.doi.org/10.1002/adma.201606380DOI Listing

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