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SS18-SSX Expression and Clinicopathologic Profiles in a Contemporary Cohort of Primary Paratesticular Synovial Sarcoma: A Series of Fourteen Patients.
Am J Surg Pathol
January 2025
Departments of Pathology, CORE Diagnostics and CORE Group of Reference Laboratories, India.
Article Synopsis
- Synovial sarcoma (SS) is a rare type of cancer, primarily found in genitourinary tissues, commonly linked to the SS18::SSX gene fusion, and its paratesticular occurrence is extremely uncommon, with only 4 documented cases prior to this study.
- This research details the characteristics and genetic profile of the largest cohort of paratesticular SS patients, analyzing data from 14 individuals aged 15 to 47, all of whom underwent surgical removal of the tumors and some received chemotherapy.
- The findings indicate a generally poor prognosis for paratesticular SS even after aggressive treatment, emphasizing the need for thorough diagnostic methods to differentiate it from similar conditions, and supporting the use of SS18-SS
Semiology and Neurophysiology of Clonic Seizures: A Report of 39 Patients.
Neurol Clin Pract
April 2024
Epilepsy Center (NF, AA, KP, AM, MV, GF-B, HL), Neurological Institute, University Hospitals Cleveland Medical Center, OH; Department of Neurology (NF, GF-B, HL), Case Western Reserve University School of Medicine; and Epilepsy Center (SH), University of Melbourne, Australia.
Background And Objectives: Clonic seizures are currently defined as repetitive and rhythmic contractions of a specific body part, producing twitching movements at a frequency of 0.2-5 Hz. There are few studies in the literature that have reported a detailed analysis of the semiology, neurophysiology, and lateralizing value of clonic seizures.
View Article and Find Full Text PDF[Hipersensibility to red tattoo ink, review of a case].
Rev Med Inst Mex Seguro Soc
July 2023
Instituto Mexicano del Seguro Social, Unidad de Alta Especialidad Centro Médico Nacional del Bajío, Servicio de Anatomía Patológica. León, Guanajuato, México.
Introduction: The hypersensitivity reaction associated with tattoo ink and its management represent a growing challenge, despite having precedents in diagnostic and treatment experience in other reports or case series in recent decades, no one has been found homogeneous offer that is effective and safe. Therefore, a review is presented with what has been described in pathophysiological theories, as well as therapeutic proposals and the response found in related cases that have been reported to date.
Clinical Case: 30-year-old male, with dermatosis located on the right upper extremity, affecting the inner side of the forearm and the outer side of the arm, unilateral, asymmetric, monomorphic in appearance, made up of an artificial macula, caused by red ink (tattoo), with development of papular-like lesions in original trace, pruritic, referred evolution time of one month.
Stellate Ganglion Blockade: an Intervention for the Management of Ventricular Arrhythmias.
Curr Hypertens Rep
October 2020
Duke Cardiology, Duke University Medical Center, 2301 Erwin Road, Durham, NC, 27710, USA.
Article Synopsis
- The review discusses the use of stellate ganglion blockade (SGB) as a treatment for patients with severe ventricular arrhythmias that don't respond to other therapies.
- SGB can significantly reduce the frequency of arrhythmias and defibrillation events for 24-72 hours, providing a critical window for additional treatments like catheter ablation or heart surgery.
- The procedure is shown to be safe, even in patients on anticoagulants, and is effective across different types and causes of ventricular arrhythmias.
Unilateral monomorphic hypopigmented macules: A variant of Darier disease.
Indian J Dermatol Venereol Leprol
November 2018
Department of Genomics and Molecular Medicine, Council of Scientific and Industrial Research-Institute of Genomics and Integrative Biology, New Delhi, India.
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