, a Member of a New Family of Plasmid-Located Quinolone Resistance Genes, Originated from the Chromosome of Enterobacter Species.

Antimicrob Agents Chemother

Servicio Antimicrobianos, Departamento de Bacteriología, Instituto Nacional de Enfermedades Infecciosas-ANLIS "Dr. Carlos G. Malbrán," Ciudad Autónoma de Buenos Aires, Argentina

Published: May 2017

, found in a clinical isolate, was undetectable by PCR assays used for the six families. was located on a conjugative plasmid (ca. 185 kb) and differed from alleles by 25%. Phylogenetic reconstructions of genes and proteins and analysis of the surroundings showed that this gene belongs to a new family and was likely mobilized by IS from the chromosome of spp. to plasmids of .

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404601PMC
http://dx.doi.org/10.1128/AAC.02555-16DOI Listing

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