Ultrasound and pulsed Doppler can assist in confirming impaired placentation looking at fetal biometry and umbilical artery Dopplers. The authors recommend confirmation of fetal wellbeing at 28-30 weeks with a PAPP-A level below the first centile.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025130PMC
http://dx.doi.org/10.1002/j.2205-0140.2012.tb00139.xDOI Listing

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