Background: The knowledge of vocal mutation is important for speech pathologists in the diagnosis and management of individuals with mutational voice disorders. However, data on vocal mutation in the Indian population are scarce and hence the present study was planned to investigate the age of attainment of vocal mutation in boys and girls from Mangalore, India, in the age range of 8-18 years.
Methods: A total of 600 participants in the age range of 8-18 years were divided into 10 groups with a 1-year interval. Sustained phonation /a/ and a narration were recorded. Two-way analysis of variance was used to obtain significant difference between the means across age and gender for the fundamental frequency and formant frequency measures.
Results: There was significant main effect of groups for fundamental frequency measure in boys, with post hoc tests revealing statistically significant differences from 14 years of age onward. However, the cutoff criteria of 140 Hz in boys and 240 Hz in girls were attained only by 16 years of age in boys and 15 years in girls, indicating that 16 and 15 years as the ages of onset of vocal mutation in boys and girls, respectively. Results also revealed that first formant frequency undergoes changes from 13 years onward. However, F2 changes from 16 years of age, with no significance observed in F3.
Conclusion: The results of the present study are useful in the assessment and management of individuals with mutational voice disorders.
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http://dx.doi.org/10.1016/j.jvoice.2016.11.019 | DOI Listing |
Front Behav Neurosci
December 2024
Department of Biology, Miami University, Oxford, OH, United States.
eNeuro
December 2024
Department of Cell Biology, Duke University Medical School, Durham, North Carolina, USA.
Epilepsy Aphasia Syndrome (EAS) is a spectrum of childhood disorders that exhibit complex co-morbidities that include epilepsy and the emergence of cognitive and language disorders. CNKSR2 is an X-linked gene in which mutations are linked to EAS. We previously demonstrated Cnksr2 knockout (KO) mice model key phenotypes of EAS analogous to those present in clinical patients with mutations in the gene.
View Article and Find Full Text PDFThis first-person essay explores wonder in the medical encounter from a patient's point of view, considering times when medical technology has given the author insight into her body and the wonder that has been evoked by these experiences. Two medical encounters are detailed: one in which post-polio vocal cord weakness was explored using a miniature camera, which evoked a sense of wonder at the process of evolution; and the second in which an MRI of the author's skull became a memento mori. The author reflects on the long processes of genetic mutation from single-celled organism to human being, and on the devolution after death to food for bacteria and insects.
View Article and Find Full Text PDFNeurosci Biobehav Rev
December 2024
Departamento de Fisiología y Desarrollo Celular, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Montes Urales 800, Miguel Hidalgo, Ciudad de México 11000, Mexico. Electronic address:
Neurol Sci
October 2024
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
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