A retrospective study extending over five years was made of the consequences of ingestion of undesirable substances by children. Despite the publicity on this subject it remains a serious medical problem. An annual average of 90 children were seen in the emergency department. Complications are caused mostly by oil products but also by drugs and household products. On average 55% of the children were hospitalized. With regard to the indication for endoscopical examination of the oesophagus and stomach after ingestion of caustic substances, insufficient arguments for performance of this examination in all children were found in the literature. We advocate a prospective study of this question. With regard to the indication for hospitalization of children after ingestion of tobacco, we are of the opinion that many children may be kept under observation in their homes after being watched for one hour.
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Eur J Med Res
December 2024
School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Infertility is a prevalent problem among 10% of people within their reproductive years. Sometimes, even advanced treatment options like assisted reproduction technology have the potential to result in failed implantation. Because of the expected changes in gene expression during both in vitro and in vivo fertilization processes, these methods of assisting fertility have also been associated with undesirable pregnancy outcomes related to infertility.
View Article and Find Full Text PDFJ Hazard Mater
December 2024
Department of Electronic Engineering, Laboratory of Micro/Nano-Optoelectronics, Xiamen University, Xiamen, Fujian 361005, China; Institute of Nanoscience and Applications (INA), Southern University of Science and Technology (SUSTech), Shenzhen 518055, China.
Managing undesirable biofilms is a persistent challenge in water treatment and distribution systems. Although ultraviolet-light emitting diode (UV-LED) irradiation, an emerging disinfection method with the chemical-free and emission-adjustable merits, has been widely reported effective to inactivate planktonic bacteria, few studies have examined its effects on biofilms. This study aims to fill this gap by exploring the performance and mechanism of UV-LEDs on the prefabricated Escherichia coli (E.
View Article and Find Full Text PDFFood Chem
December 2024
School of Life Science, Jiangxi Science &Technology Normal University, Nanchang 330013, China.
In this study, the dynamic effects of ultrasonic treatment (0-400 W) on the volatile flavor compounds of pumpkin juice under different storage periods were investigated systematically using a combination of headspace solid-phase microextraction gas chromatography-mass spectrometry (HS-SPME-GC-MS) and gas chromatography-ion mobility spectrometry (GC-IMS) techniques. A total of 139 and 46 volatile organic compounds (VOCs) were identified by GC-MS and GC-IMS, respectively. The results indicated that complex changes in volatile components occurred during storage.
View Article and Find Full Text PDFBehav Pharmacol
February 2025
Department of Pharmacology, Biological Sciences Sector, Federal University of Paraná.
Opioid use disorder is a public health problem that includes symptoms such as withdrawal syndrome and opioid-induced hyperalgesia. Currently, drugs to treat side effects of opioids also have undesirable effects, which lead to limitations. This study investigated the effect of a treatment with cannabidiol in morphine-induced hyperalgesia and withdrawal behavior in morphine-dependent rats.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Department of Pharmaceutical Chemistry, M.R. College of Pharmaceutical Sciences and Research, Balisha-743234, India. Electronic address:
With cancer rates on the rise around the world, cancer treatment has dominated scientific discussions in recent years. The toxicity of cytotoxic drugs, their lack of tumor localization, and their uniform dispersion into tumor tissues are the obstacles to cancer therapy. Other cancer treatment drawbacks include short blood circulation half-lives and undesirable pharmacokinetic behavior.
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