Background: Follicular lipidosis is a rare disease, having only been reported in six Rottweiler dogs. The diagnosis of follicular lipidosis is confirmed by histopathological examination of the affected skin.
Objective: To report a case of follicular lipidosis in a dachshund dog.
Animals: A 13-month-old female dachshund dog, with hypotrichosis on the head and cervical region from 10 months of age.
Methods: Histological examination of skin biopsy specimens.
Results: Histological examination revealed basket weave orthokeratosis, ballooning of matrix cells and external root sheath keratinocytes.
Clinical Importance: This case report highlights the importance of including follicular lipidosis among the differential diagnoses of noninflammatory and nonhormonal cutaneous lesions in dachshund presented with hair loss.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/vde.12424 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effects of long-term dehydration on stress markers, blood parameters, and tissue morphology in the dromedary camel ().
Front Vet Sci
December 2023
Department of Pharmacology, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain, United Arab Emirates.
Introduction: Dromedary camels robustly withstand dehydration, and the rough desert environment but the adaptation mechanisms are not well understood. One of these mechanisms is that the dromedary camel increases its body temperature to reduce the process of evaporative cooling during the hot weather. Stress in general, has deleterious effects in the body.
View Article and Find Full Text PDFCharacterization of peripheral blood T follicular helper (TFH) cells in patients with type 1 Gaucher disease and carriers.
Blood Cells Mol Dis
May 2023
Department of Medical Biology, Medical Faculty, Erciyes University, 38030 Kayseri, Turkey; Betül-Ziya Eren Genome and Stem Cell Research Center, Erciyes University, 38030 Kayseri, Turkey.
Background: Gaucher disease (GD) is the most common autosomal recessive lipid storage disease. In this study, the changes in TFH cells and IL-4 and IL-21 cytokines in blood samples of GD patients, carriers and healthy volunteers were investigated.
Methods: Two pretreatment type 1 GD patients, 20 currently treated type 1 GD patients, 6 carriers, and 27 healthy volunteers were enrolled in the study.
Lysosomal Storage Disorders and Malignancy.
Diseases
February 2017
Royal Free London NHS Foundation Trust, University College London, London NW3 2QG, UK.
Lysosomal storage disorders (LSDs) are infrequent to rare conditions caused by mutations that lead to a disruption in the usual sequential degradation of macromolecules or their transit within the cell. Gaucher disease (GD), a lipidosis, is among the most common LSD, with an estimated incidence of 1 in 40,000 among the Caucasian, non-Jewish population. Studies have indicated an increased frequency of polyclonal and monoclonal gammopathy among patients with GD.
View Article and Find Full Text PDFFollicular lipidosis in a dachshund dog.
Vet Dermatol
August 2017
Graduate Program in Veterinary Pathology and Cytopathology, Department of Veterinary Medicine, School of Veterinary Medicine, Anhembi Morumbi University, R. Drive Almeida Lima, 1134 - Parque da Mooca, 03164-000, São Paulo, SP, Brazil.
Background: Follicular lipidosis is a rare disease, having only been reported in six Rottweiler dogs. The diagnosis of follicular lipidosis is confirmed by histopathological examination of the affected skin.
Objective: To report a case of follicular lipidosis in a dachshund dog.
Type II NKT-TFH cells against Gaucher lipids regulate B-cell immunity and inflammation.
Blood
February 2015
Section of Hematology and Yale Cancer Center, Yale University School of Medicine, New Haven, CT.
Chronic inflammation including B-cell activation is commonly observed in both inherited (Gaucher disease [GD]) and acquired disorders of lipid metabolism. However, the cellular mechanisms underlying B-cell activation in these settings remain to be elucidated. Here, we report that β-glucosylceramide 22:0 (βGL1-22) and glucosylsphingosine (LGL1), 2 major sphingolipids accumulated in GD, can be recognized by a distinct subset of CD1d-restricted human and murine type II natural killer T (NKT) cells.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!