Objective: The Health and Social Care Act 2012 ('HSCA 2012') introduced a new, statutory, form of regulation of competition into the National Health Service (NHS), while at the same time recognising that cooperation was necessary. NHS England's policy document, The Five Year Forward View ('5YFV') of 2014 placed less emphasis on competition without altering the legislation. We explored how commissioners and providers understand the complex regulatory framework, and how they behave in relation to competition and cooperation.
Design: We carried out detailed case studies in four clinical commissioning groups, using interviews and documentary analysis to explore the commissioners' and providers' understanding and experience of competition and cooperation.
Setting/participants: We conducted 42 interviews with senior managers in commissioning organisations and senior managers in NHS and independent provider organisations (acute and community services).
Results: Neither commissioners nor providers fully understand the regulatory regime in respect of competition in the NHS, and have not found that the regulatory authorities have provided adequate guidance. Despite the HSCA 2012 promoting competition, commissioners chose mainly to use collaborative strategies to effect major service reconfigurations, which is endorsed as a suitable approach by providers. Nevertheless, commissioners are using competitive tendering in respect of more peripheral services in order to improve quality of care and value for money.
Conclusions: Commissioners regard the use of competition and cooperation as appropriate in the NHS currently, although collaborative strategies appear more helpful in respect of large-scale changes. However, the current regulatory framework contained in the HSCA 2012, particularly since the publication of the 5YFV, is not clear. Better guidance should be issued by the regulatory authorities.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306513 | PMC |
http://dx.doi.org/10.1136/bmjopen-2016-011745 | DOI Listing |
Chemistry
March 2025
Chinese Academy of Sciences Fujian Institute of Research on the Structure of Matter, State Key Laboratory of Structural Chemistry, CHINA.
Dimethyl carbonate and dimethyl oxalate are competitive products of the carbonylation reaction of methyl nitrite (MN) under Pd-based catalysts. The chemo-selectivity is influenced not just by the thermodynamic constraints of reaction conditions but also by the electronic structures of catalysts. Lewis acid sites are extensively employed to modulate the electronic structures of Pd active sites for kinetic carbonate production, but their precise role remains unclear.
View Article and Find Full Text PDFSci Rep
March 2025
Psychology Research Center (CIPsi), School of Psychology, University of Minho, Braga, Portugal.
Interpersonal synchrony refers to the temporal coordination between two individuals, signaling the coupling of their behaviors. Optimal movement synchrony in dyads is linked to more affiliative behavior, cooperation, and trust. However, there is limited research on how the sensory environment impacts interpersonal synchrony.
View Article and Find Full Text PDFChemistry
March 2025
Xi'an University of Science and Technology, College of Chemistry and Chemical Engineering, No. 58 Yanta Road, 710054, Xi'an, CHINA.
Chiral competition between carbohydrates and amino acids is crucial for understanding homochirality emergence in biological systems. In this study, the chiral competitive effect between carbohydrates and amino acids through the host-guest complex formation was investigated by employing amino acid modified pyrene derivatives and naturally occurring γ-cyclodextrin (γ-CD) as chiral sources, the circularly polarized luminance (CPL) as indicator. Supramolecular complexes of achiral 1-pyrenebutyric acid and L-amino acid-pyrene derivatives with γ-CD exhibited positive CPL signals, which chirality derived from γ-CD's stereochirality.
View Article and Find Full Text PDFThis review focuses on the interactions between the cutaneous senses, and in particular touch and temperature, as these are the most relevant for developing skin-based display technologies for use in virtual reality (VR) and for designing multimodal haptic devices. A broad spectrum of research is reviewed ranging from studies that have examined the mechanisms involved in thermal intensification and tactile masking, to more applied work that has focused on implementing thermal-tactile illusions such as thermal referral and illusory wetness in VR environments. Research on these tactile-thermal illusions has identified the differences between the senses of cold and warmth in terms of their effects on the perception of object properties and the prevalence of the perceptual experiences elicited.
View Article and Find Full Text PDFOncogene
March 2025
Biomedical Research in Melanoma-Animal Models and Cancer Laboratory-Vall d´Hebron Research Institute VHIR-Vall d'Hebron Hospital-UAB, Barcelona, Spain.
The mechanisms behind UVB-initiated, neonatal-specific melanoma linked to BRAF are not well understood, particularly regarding its role in growth arrest. We found that, beyond mutations, neonatal UV irradiation or Lkb1 loss promotes a cell-autonomous transcriptional reprogramming that prevents BRAF-induced growth arrest, leading to melanoma development. Using UVB-dependent and independent mouse models, genomic analyses, clinical data, and single-cell transcriptomics, we identified a transcriptional program that bypasses growth arrest, promoting melanoma.
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