A case of a chronic lung berylliosis in a 20-year-old woman with a 20-weeks pregnancy is described. The diagnosis is established on the basis of morphological features: fibrosing alveolitis with numerous lympho-histiocytic granulomas containing conchoidal bodies and the lung tissue chemical analysis showing the presence of beryllium (2.71 X 10(-6) g/organ). Morphology of the lungs is described in detail.
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Am J Ind Med
January 2025
Division of Environmental and Occupational Health Sciences, Department of Medicine, National Jewish Health, Denver, Colorado, USA.
Background: Despite the utility of the beryllium lymphocyte proliferation test (BeLPT), distinguishing sarcoidosis, a disease of unknown etiology, from chronic beryllium disease (CBD), has long posed a diagnostic challenge. It is unclear if beryllium-exposed sarcoidosis cases (Be-exp-Sarc) are clinically distinct from CBD, or are misdiagnosed cases of CBD.
Methods: We performed a case-case study of 40 beryllium-exposed individuals diagnosed with Be-exp-Sarc compared to 40 frequency-matched CBD cases.
Thorax
October 2024
Thoracic Surgery, SLK-Lungenklinik Lowenstein, Lowenstein, Germany.
Int J Mol Sci
July 2024
Department of Nephrology and Dialysis, Brugmann University Hospital, Université libre de Bruxelles, 1020 Bruxelles, Belgium.
J Occup Environ Med
March 2024
From the Division of Occupational and Environmental Medicine, Department of Medicine, College of Human Medicine, Michigan State University, East Lansing, MI (H.T., L.W., K.D.R.); and Materion Brush, Inc, Elmore, OH (C.D.).
Objective: The aim of the study is to investigate the cause of death among individuals diagnosed with chronic beryllium disease (CBD) or beryllium sensitization (BeS).
Methods: Vital status, cause of death, and standardized mortality ratios for the underlying cause of death were determined for a cohort of 354 individuals with CBD and 290 individuals with BeS.
Results: Among 216 deceased individuals, 153 had CBD and 63 had BeS.
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