A new nosological entity of slow infections provoked by noncanonical viruses was experimentally studied. It was shown that natural human infection and infection induced in guinea pigs had common clinical and morphological parameters and were characterized by severe changes in the central nervous system. Histologically, the death of the motoneurones of the spinal cord, the spongious state of the white matter of the brain and spinal cord, relative preservation of myelin, hypertrophy and proliferation of macroglia were histologically observed.
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